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현미에서 배양된 차가버섯 분말의 영양성분과 제2형 당뇨환자의 건강지표 및 혈당관련인자에 미치는 영향

Nutrition Contents and Health Status, Blood Glucose Response Effect for NIDDM Patients of Inonotus Obliquus in Culturing Method by Using Unpolished Rice

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참고문헌

주제분류한의학

초록

본 연구는 여러 가지 기능성 성분을 함유하고 있다고 알려진 차가버섯이 혈당관리에 기여할 수 있는지를 임상실험을 통해 알아보고자 계획수행되었다. 즉, 차가버섯 균사체 배양용 배지로 가식성인 현미를 이용하여 배양한 차가버섯 분말을 제2형 당뇨병을 지닌 환자들에게 섭취시켜 혈액학적 성상과 혈중 당뇨관련 지표 물질들의 농도 변화를 관찰하여 고혈당이나 당뇨환자들에게 적용할 수 있는 기능성 식품의 소재로의 개발 가능성을 알아보고자 하였다. 그 결과, 제2형 당뇨환자들이 10주간 매일 75g의 차가버섯 분말을 섭취했을 때 건강상태, 공복시 혈당 및 혈당관련 요인에 유익한 영향을 주어 혈당관리를 위해 활용이 가능함을 타진할 수 있었다. 그 기전이나 섭취량에 관한 연구는 동물실험을 통한 dose-respone effect를 조사한다면 명확히 알 수 있으리라 판단되나 제2형 당뇨환자들의 적정량 꾸준한 섭취는 혈당저하 및 건강증진에 도움을 줄 수 있다고 제안할 수 있겠다.또한 본 결과를 차가버섯을 이용한 기능성 식품이나 건강식품의 개발에 활용할 수 있으리라 사료된다.

Abstract

The purpose of this study was to investigate the possibility of Inonotus obliquus as an functional resource. To assess the effects of Inonotus obliquus in culturing method by using unpolished rice in 15non-insulin dependent diabetes mellitus persons, we examined changes of hematological and chemical variables, DM indices content in serum during the Inonotus obliquus supplementation. GOT, GPT concentrations were significantly decreased. But TIBC content was significantly increased. Fasting glucose level during Inonotus obliquus supplementation was decreased respectively. These results show that modest dose of Inonotus obliquus in culturing method by using unpolished rice supplementation can decrease fasting blood glucose level without any changes in health indices and nutrition status of the non-insulin dependent diabetes mellitus person. These results indicated that Inonotus obliquus in culturing method by using unpolished rice diet is effective therapeutic regimen for the control of metabolic derangements in diabetes mellitus. Also, the results imply that Inonotus obliquus in culturing method by using unpolished rice can be used as possible functional food materials. However, large amounts of Inonotus obliquus in culturing method by using unpolished rice showed be used cautiously application.

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