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아주까리 메탄올 추출물의 항산화 효과 및 아질산염 소거작용

Antioxidative Activity and Nitrite Scavenging Ability of Methanol Extract from Ricinus communis

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주제분류한의학

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Abstract

Efficacy of antioxidative activity and nitrite scavenging ability of methanol extract from Ricinus communis. was investigated. Electron-donating ability of extract at RC50 was 114.02 ㎍/mL. After addition of 0.46 ㎎/mL extract, autoxidation of pyrogallol decreased to 32.99% by superoxide dismutase-like activity. In antioxidative activity of extract against linoleic acid during incubation times of 24, 48, 96 hours at 40℃, lipid peroxidation values significantly decreased by 85.50%, 87.77%, 90.95% with addition of 0.2 ㎎/mL, respectively. Total phenolic content was determined as gallic acid equivalents (GAE) and values revealed 83.98 ± 5.66 GAE ㎍/㎎ of extract. Nitrite scavenging ability showed the most remarkable effect at pH 1.2, decreasing to 47.24% by addition of 0.2 ㎎/mL. These results suggest that methanol extract from Ricinus communis. can be used as bioactive and functional material.

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