본문 바로가기
KERD
논문KCI 등재

용육조위탕 증류액이 노화 흰쥐의 간세포 및 비장세포의 항산화능에 미치는 영향

Anti-Oxidative Effect of Yongyukjowi-tang Distillate on Liver and Spleen Cells of Aged Rats

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류한의학

초록

The purpose of this study is to investigate the anti-oxidative effect of Yongyukjowi-tang (YJT) distillate on liver and spleen cells of aged rats. This experiment was performed using liver and spleen cells of 10w, 52w, 72w old SD rats. The cells were divided into three groups; DW, Vit.C, and YJT groups, which were treated with distilled water, vitamin C, and YJT distillate respectively, and the levels of Superoxide Dismutase (SOD) and malondialdehyde (MDA) were measured. SOD level in liver and spleen cells of 10w old rats was significantly increased in YJT group compared to DW group. MDA level in liver cells of 72w old rats was significantly decreased in YJT group compared to DW group. Yongyukjowi-tang distillate showed an anti-oxidative effect on liver and spleen cells of aged rats.

Abstract

The purpose of this study is to investigate the anti-oxidative effect of Yongyukjowi-tang (YJT) distillate on liver and spleen cells of aged rats. This experiment was performed using liver and spleen cells of 10w, 52w, 72w old SD rats. The cells were divided into three groups; DW, Vit.C, and YJT groups, which were treated with distilled water, vitamin C, and YJT distillate respectively, and the levels of Superoxide Dismutase (SOD) and malondialdehyde (MDA) were measured. SOD level in liver and spleen cells of 10w old rats was significantly increased in YJT group compared to DW group. MDA level in liver cells of 72w old rats was significantly decreased in YJT group compared to DW group. Yongyukjowi-tang distillate showed an anti-oxidative effect on liver and spleen cells of aged rats.

참고문헌 (24)

  1. The Korean Academy of Family Medicine, "Textbook of Family Medicine", pp.300~ (2007), Hankookbook
  2. Harman D. Aging, "A theory based on free radical radiation chemistry", J Gerontal, 11, pp.298~300 (1956)
  3. Cohen, G., "The generation of hydroxyl radicals in biologic systems : toxicological aspects", Photochem Photobiol, 28(d4-5) (1978)
  4. Cutler, R.G., "Free Radicals in Biology", pp.371~424 (1984), Academic Press
  5. Son, J.R., "Free Radical and Antioxidant", pp.26~29 (2004), Biomedical
  6. Oriental Physiology Compilation Committee of Korean Oriental Medical Colleges, "Korean Oriental Physiology", pp.481~ (2008), Jipmoondang
  7. Hebeiyixueyuan, "Lingshujingjiaoshi", pp.355~ (1982), People’s medical publishing house
  8. Cheng, Sh.D., "Suwenzhuyihuicui", pp.95~ (1987), People’s medical publishing house
  9. Won, J.S., "Dongui Sasang Shinpyun", pp.232~ (2002), Jeongdam
  10. Han-Eol Lee, "The Effect of Oral Administration of Yongyukjowi-tang on the Immune Activity in Aged Rat", Journal of Sasang Constitutional Medicine, 24(4), pp.62~74 (2012), The Society of Sasang Constitutional Medicine[DOI]
  11. Yoo, S.H., "The Health of Korean Old Age", pp.28~34 (2001), Sohwa
  12. Vinay, K., "Robbins Basic Pathology", pp.16~ (2007), Elsevier
  13. Textbook Compilation Committee For Korean Medicine Neuropsychiatry, "Korean Medicine Neuropsychiatry", pp.443~ (2007), Jipmoondang
  14. A college of Korean medicine Association of Sasang medicine lecture room sewing, "Sasang Medicine", pp.311~315 (2004), Jipmoondang
  15. Lee, E. J., "A study of Aging and Life Span in Sasang Constitutional Medicine", J Sasang Constitut Med, 14(3), pp.7~16 (2002)
  16. Lee, S. I., "Herbal medicine clinical applications", pp.366~419 (1986), Seongbo publishing
  17. Herbology Textbook Compilation Commitee for College of Korean Medicine, "Herbology", pp.534~720 (2008), Yeonglim
  18. Jin-Wook Yi, "The Effect of Yongyukjowitang Distillate on the Immune Activity of Spleen Cells of Aged Rats", Journal of Sasang Constitutional Medicine, 25(3), pp.218~232 (2013), The Society of Sasang Constitutional Medicine[DOI]
  19. Kim, Y. B., "Age-related Changes of Antioxidative Ability, Physiological and Behavioral Characteristics in Senescence Accelerated Mouse", Korean J Gerontology, 5(2), pp.80~87 (1995)
  20. Lee, G. N., "Clinical Pathology File", pp.193~345 (2003), MEDrang
  21. Sakamoto, Y., "Glutathione", pp.5~ (1989), Jodhpur, Scientific
  22. Pál, P., "Nitric Oxide and Peroxynitrite in Health and Disease", Physiol Rev, 87(1), pp.315~424 (2007)
  23. Maxwell, S. R., "Changes in Plasma Antioxidant Status During Eccentric Exercise and the Effect of Vitamin Supplementation", Free Radic Res Commun, 19(3), pp.191~202 (1993)
  24. 이미숙, "한국산 5종 해조류의 항산화효과와 총 폴리페놀 함량과의 관련성", 한국식품영양과학회지, 34(8), pp.1143~1150 (2005), 한국식품영양과학회

관련 논문AI추천

이 간행물의 다른 논문 (8건)