용육조위탕 증류액이 노화 흰쥐의 간세포 및 비장세포의 항산화능에 미치는 영향
Anti-Oxidative Effect of Yongyukjowi-tang Distillate on Liver and Spleen Cells of Aged Rats
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The purpose of this study is to investigate the anti-oxidative effect of Yongyukjowi-tang (YJT) distillate on liver and spleen cells of aged rats. This experiment was performed using liver and spleen cells of 10w, 52w, 72w old SD rats. The cells were divided into three groups; DW, Vit.C, and YJT groups, which were treated with distilled water, vitamin C, and YJT distillate respectively, and the levels of Superoxide Dismutase (SOD) and malondialdehyde (MDA) were measured. SOD level in liver and spleen cells of 10w old rats was significantly increased in YJT group compared to DW group. MDA level in liver cells of 72w old rats was significantly decreased in YJT group compared to DW group. Yongyukjowi-tang distillate showed an anti-oxidative effect on liver and spleen cells of aged rats.
Abstract
The purpose of this study is to investigate the anti-oxidative effect of Yongyukjowi-tang (YJT) distillate on liver and spleen cells of aged rats. This experiment was performed using liver and spleen cells of 10w, 52w, 72w old SD rats. The cells were divided into three groups; DW, Vit.C, and YJT groups, which were treated with distilled water, vitamin C, and YJT distillate respectively, and the levels of Superoxide Dismutase (SOD) and malondialdehyde (MDA) were measured. SOD level in liver and spleen cells of 10w old rats was significantly increased in YJT group compared to DW group. MDA level in liver cells of 72w old rats was significantly decreased in YJT group compared to DW group. Yongyukjowi-tang distillate showed an anti-oxidative effect on liver and spleen cells of aged rats.
참고문헌 (24)
- The Korean Academy of Family Medicine, "Textbook of Family Medicine", pp.300~ (2007), Hankookbook
- Harman D. Aging, "A theory based on free radical radiation chemistry", J Gerontal, 11, pp.298~300 (1956)
- Cohen, G., "The generation of hydroxyl radicals in biologic systems : toxicological aspects", Photochem Photobiol, 28(d4-5) (1978)
- Cutler, R.G., "Free Radicals in Biology", pp.371~424 (1984), Academic Press
- Son, J.R., "Free Radical and Antioxidant", pp.26~29 (2004), Biomedical
- Oriental Physiology Compilation Committee of Korean Oriental Medical Colleges, "Korean Oriental Physiology", pp.481~ (2008), Jipmoondang
- Hebeiyixueyuan, "Lingshujingjiaoshi", pp.355~ (1982), People’s medical publishing house
- Cheng, Sh.D., "Suwenzhuyihuicui", pp.95~ (1987), People’s medical publishing house
- Won, J.S., "Dongui Sasang Shinpyun", pp.232~ (2002), Jeongdam
- Han-Eol Lee, "The Effect of Oral Administration of Yongyukjowi-tang on the Immune Activity in Aged Rat", Journal of Sasang Constitutional Medicine, 24(4), pp.62~74 (2012), The Society of Sasang Constitutional Medicine[DOI]
- Yoo, S.H., "The Health of Korean Old Age", pp.28~34 (2001), Sohwa
- Vinay, K., "Robbins Basic Pathology", pp.16~ (2007), Elsevier
- Textbook Compilation Committee For Korean Medicine Neuropsychiatry, "Korean Medicine Neuropsychiatry", pp.443~ (2007), Jipmoondang
- A college of Korean medicine Association of Sasang medicine lecture room sewing, "Sasang Medicine", pp.311~315 (2004), Jipmoondang
- Lee, E. J., "A study of Aging and Life Span in Sasang Constitutional Medicine", J Sasang Constitut Med, 14(3), pp.7~16 (2002)
- Lee, S. I., "Herbal medicine clinical applications", pp.366~419 (1986), Seongbo publishing
- Herbology Textbook Compilation Commitee for College of Korean Medicine, "Herbology", pp.534~720 (2008), Yeonglim
- Jin-Wook Yi, "The Effect of Yongyukjowitang Distillate on the Immune Activity of Spleen Cells of Aged Rats", Journal of Sasang Constitutional Medicine, 25(3), pp.218~232 (2013), The Society of Sasang Constitutional Medicine[DOI]
- Kim, Y. B., "Age-related Changes of Antioxidative Ability, Physiological and Behavioral Characteristics in Senescence Accelerated Mouse", Korean J Gerontology, 5(2), pp.80~87 (1995)
- Lee, G. N., "Clinical Pathology File", pp.193~345 (2003), MEDrang
- Sakamoto, Y., "Glutathione", pp.5~ (1989), Jodhpur, Scientific
- Pál, P., "Nitric Oxide and Peroxynitrite in Health and Disease", Physiol Rev, 87(1), pp.315~424 (2007)
- Maxwell, S. R., "Changes in Plasma Antioxidant Status During Eccentric Exercise and the Effect of Vitamin Supplementation", Free Radic Res Commun, 19(3), pp.191~202 (1993)
- 이미숙, "한국산 5종 해조류의 항산화효과와 총 폴리페놀 함량과의 관련성", 한국식품영양과학회지, 34(8), pp.1143~1150 (2005), 한국식품영양과학회
