소화성 궤양을 동반한 경피골막증 1예
A case of pachydermoperiostosis with peptic ulcer disease
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초록
본 증례는 말단비대증이 의심되어 입원하였으나, 경피골막증으로 진단되었고, 상부위장관 출혈을 동반하여 항소화성 궤양 치료제로 치유된 1예를 경험하였기에 보고하는 바이다.
Abstract
We experienced a Korean patient with complete form of pachydermoperiostosis. He presented with typical features consisting of clubbing with spade like enlargement of the hand and feet, thickening of facial skin and scalp, irregular thickening of cortex with periosteal new bone formation involving radii, ulnae, tibiae, and fibulae. Classically, pachydermoperiostosis is characterized by a triad of finger clubbing, periostitis, skin and soft tissue changes, giving an acromegaloid look. A variety of associated abnormalities have been described such as cranial suture defects, female escutcheon, bone marrow failure. There are a few reports documenting gastric ulcer, hypertrophic gastropathy and Crohn's disease as accompanying diseases. The patient had upper gastrointestinal bleeding caused by hemorrhagic gastritis and duodenal ulcer. A case is herein reported of pachydermoperiostosis accompanied by peptic ulcer disease.(Korean J Med 63:329-334, 2002)