New Diagnostic Approach for Esophageal Squamous Cell Neoplasm Using Linked Color Imaging and Blue Laser Imaging Combined with Iodine Staining
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A 62-year-old man with a flat early esophageal cancer was referred for endoscopic treatment. White light imaging revealed a pale redlesion, whereas linked color imaging (LCI) and blue laser imaging (BLI) yielded purple and brown images, respectively. Iodine stainingdemonstrated a large unstained area with a homogenous but very weak pink-color sign. This area appeared more clearly as purpleand green on LCI and BLI, respectively; however, a different colored portion was observed at the 4 o’clock position inside the iodineunstainedarea. Histopathology findings of the resected specimen revealed squamous intraepithelial neoplasia at the 4 o’clock positionand an esophageal squamous cell carcinoma in the remaining iodine-unstained area. LCI and BLI combined with iodine stainingproduce characteristic images that overcomes the pink-color sign, reflecting the histological features of a flat esophageal neoplasm. Thisnew method is useful for detailed evaluation of early flat squamous cell neoplasms.
Abstract
A 62-year-old man with a flat early esophageal cancer was referred for endoscopic treatment. White light imaging revealed a pale redlesion, whereas linked color imaging (LCI) and blue laser imaging (BLI) yielded purple and brown images, respectively. Iodine stainingdemonstrated a large unstained area with a homogenous but very weak pink-color sign. This area appeared more clearly as purpleand green on LCI and BLI, respectively; however, a different colored portion was observed at the 4 o’clock position inside the iodineunstainedarea. Histopathology findings of the resected specimen revealed squamous intraepithelial neoplasia at the 4 o’clock positionand an esophageal squamous cell carcinoma in the remaining iodine-unstained area. LCI and BLI combined with iodine stainingproduce characteristic images that overcomes the pink-color sign, reflecting the histological features of a flat esophageal neoplasm. Thisnew method is useful for detailed evaluation of early flat squamous cell neoplasms.
참고문헌 (18)
- Wang J, "The symptom-to-treatment delay and stage at the time of treatment in cancer of esophagus", Jpn J Clin Oncol, 38, pp.87~91 (2008)
- Ishihara R, "Prospective evaluation of narrow-band imaging endoscopy for screening of esophageal squamous mucosal high-grade neoplasia in experienced and less experienced endoscopists", Dis Esophagus, 23, pp.480~486 (2010)
- Muto M, "Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging : a multicenter randomized controlled trial", J Clin Oncol, 28, pp.1566~1572 (2010)
- Yokoyama A, "Is it proper to use non-magnified narrow-band imaging for esophageal neoplasia screening? Japanese single-center, prospective study", Dig Endosc, 24, pp.412~418 (2012)
- Ebi M, "Multicenter, prospective trial of white-light imaging alone versus white-light imaging followed by magnifying endoscopy with narrow-band imaging for the real-time imaging and diagnosis of invasion depth in superficial esophageal squamous cell carcinoma", Gastrointest Endosc, 81, pp.1355~1361 (2015)
- Tomie A, "Blue laser imaging-bright improves endoscopic recognition of superficial esophageal squamous cell carcinoma", Gastroenterol Res Pract, 2016, pp.6140854~ (2016)
- Diao W, "Diagnostic ability of blue laser imaging combined with magnifying endoscopy for early esophageal cancer", Dig Liver Dis, 50, pp.1035~1040 (2018)
- Osawa H, "Blue laser imaging provides excellent endoscopic images of upper gastrointestinal lesions", Video Journal and Encyclopedia of GI Endoscopy, 1, pp.607~610 (2014)
- Ishihara R, "Quantitative analysis of the color change after iodine staining for diagnosing esophageal high-grade intraepithelial neoplasia and invasive cancer", Gastrointest Endosc, 69, pp.213~218 (2009)
- Goda K, "Narrow-band imaging magnifying endoscopy versus Lugol chromoendoscopy with pink-color sign assessment in the diagnosis of superficial esophageal squamous neoplasms : a randomised noninferiority trial", Gastroenterol Res Pract, 2015, pp.639462~ (2015)
- Oyama T, "Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology : magnifying endoscopic classification of the Japan Esophageal Society", Esophagus, 14, pp.105~112 (2017)
- Kuehni RG, "Color-tolerance data and the tentative CIE 1976 L a b formula", J Opt Soc Am, 66, pp.497~500 (1976)
- Shimizu Y, "Endoscopic diagnosis of early squamous neoplasia of the esophagus with iodine staining : high-grade intra-epithelial neoplasia turns pink within a few minutes", J Gastroenterol Hepatol, 23, pp.546~550 (2008)
- Nagami Y, "Usefulness of non-magnifying narrow-band imaging in screening of early esophageal squamous cell carcinoma : a prospective comparative study using propensity score matching", Am J Gastroenterol, 109, pp.845~854 (2014)
- Maselli R, "The metallic silver sign with narrow-band imaging : a new endoscopic predictor for pharyngeal and esophageal neoplasia", Gastrointest Endosc, 78, pp.551~553 (2013)
- Osawa H, "Diagnosis of depressed-type early gastric cancer using small-caliber endoscopy with flexible spectral imaging color enhancement", Dig Endosc, 24, pp.231~236 (2012)
- Fukuda H, "Linked color imaging can enhance recognition of early gastric cancer by high color contrast to surrounding gastric intestinal metaplasia", J Gastroenterol (2018)[DOI]
- Hiroyuki Osawa, "Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening", Clinical Endoscopy, 51(6), pp.513~526 (2018), 대한소화기내시경학회