Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening
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초록
White light imaging (WLI) may not reveal early upper gastrointestinal cancers. Linked color imaging (LCI) produces bright imagesin the distant view and is performed for the same screening indications as WLI. LCI and blue laser imaging (BLI) provide excellentvisibility of gastric cancers in high color contrast with respect to the surrounding tissue. The characteristic purple and green colorof metaplasias on LCI and BLI, respectively, serve to increase the contrast while visualizing gastric cancers regardless of a history ofHelicobacter pylori eradication. LCI facilitates color-based recognition of early gastric cancers of all morphological types, including flat lesions or those in an H. pylori-negative normal background mucosa as well as the diagnosis of inflamed mucosae including erosions. LCI reveals changes inmucosal color before the appearance of morphological changes in various gastric lesions. BLI is superior to LCI in the detection ofearly esophageal cancers and abnormal findings of microstructure and microvasculature in close-up views of upper gastrointestinalcancers. Excellent images can also be obtained with transnasal endoscopy. Using a combination of these modalities allows one to obtainimages useful for establishing a diagnosis. It is important to observe esophageal cancers (brown) using BLI and gastric cancers (orange)surrounded by intestinal metaplasia (purple) and duodenal cancers (orange) by LCI.
Abstract
White light imaging (WLI) may not reveal early upper gastrointestinal cancers. Linked color imaging (LCI) produces bright imagesin the distant view and is performed for the same screening indications as WLI. LCI and blue laser imaging (BLI) provide excellentvisibility of gastric cancers in high color contrast with respect to the surrounding tissue. The characteristic purple and green colorof metaplasias on LCI and BLI, respectively, serve to increase the contrast while visualizing gastric cancers regardless of a history ofHelicobacter pylori eradication. LCI facilitates color-based recognition of early gastric cancers of all morphological types, including flat lesions or those in an H. pylori-negative normal background mucosa as well as the diagnosis of inflamed mucosae including erosions. LCI reveals changes inmucosal color before the appearance of morphological changes in various gastric lesions. BLI is superior to LCI in the detection ofearly esophageal cancers and abnormal findings of microstructure and microvasculature in close-up views of upper gastrointestinalcancers. Excellent images can also be obtained with transnasal endoscopy. Using a combination of these modalities allows one to obtainimages useful for establishing a diagnosis. It is important to observe esophageal cancers (brown) using BLI and gastric cancers (orange)surrounded by intestinal metaplasia (purple) and duodenal cancers (orange) by LCI.
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