B형간염보균자에서 발생한 A형간염에 의한 전격간부전 1예
A case of fulminant hepatic failure complicating hepatitis A virus superinfection in a hepatitis B virus carrier
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초록
A형간염은 급성 간염 후 대부분 완치되고 만성화는 되지 않지만 약 0.1%에서 간부전이 발생하며 다른 바이러스간염이나 만성 간질환자에게서 간부전의 위험성이 증가한다. 최근 A형간염이 급격히 증가하면서 B형 및 C형간염 등 만성 간질환이 흔한 우리나라에서 HAV 중복감염으로 인한 전격간부전이 우려되고 있다. 저자들은 B형간염보균자에서 HAV 중복감염으로 급격히 간부전이 발생하여 내원 9일만에 사망한 증례를 경험하여 보고하는 바이다.
Abstract
Hepatitis A virus (HAV) is invariably a self-limited infection, with the majority of patients recovering completely. Underlying chronic liver disease and old age are associated with increased severity and an increased risk of fulminant hepatic failure. We report a case of fulminant hepatic failure caused by HAV superinfection in a 36-year-old male hepatitis B carrier. Recently, the incidence of acute hepatitis A in Korean adults has been increasing. Furthermore, Korea is an endemic area for chronic liver disease, including hepatitis B and C. Therefore, the risk of progression to acute fulminant hepatic failure should be considered for hepatitis A patients with impaired liver function, especially with underlying chronic liver disease.
참고문헌 (18)
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