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논문KCI 등재

IgA 신증 40여 년

IgA nephropathy over 40 years

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참고문헌

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초록

IgA nephropathy is characterized by the predominant deposition of IgA in a granular fashion diffusely in the mesangial zones of glomeruli. IgA nephropathy was first described over four decades ago and is now the most common form of primary glomerular disease. Much progress has been made in the elucidation of potential pathogenetic mechanisms such as undergalactosylated IgA1 as well as in the fields of clinical features, prognosis, and treatment. This knowledge is being applied in the development of new diagnostic methods and hopefully in the future the creation of novel and rational therapeutic approaches.

Abstract

IgA nephropathy is characterized by the predominant deposition of IgA in a granular fashion diffusely in the mesangial zones of glomeruli. IgA nephropathy was first described over four decades ago and is now the most common form of primary glomerular disease. Much progress has been made in the elucidation of potential pathogenetic mechanisms such as undergalactosylated IgA1 as well as in the fields of clinical features, prognosis, and treatment. This knowledge is being applied in the development of new diagnostic methods and hopefully in the future the creation of novel and rational therapeutic approaches.

참고문헌 (70)

  1. Berger J, "Ses Depots intracapillaires d’IgA-IgG", J Urol, 73, pp.694~695 (1968)
  2. 대한신장학회 등록위원회, "우리나라 신대체 요법의 현황", ~ (2007)
  3. Galla JH, "IgA nephropathy", Kidney Int, 47, pp.377~387 (1995)
  4. Simon P, "Epidemiologic data of primary glomerular diseases in western France", Kidney Int, 66, pp.905~908 (2004)
  5. 김명재, "IgA nephropathy의 병리조직학적 검색", 대한신장학회잡지, 4, pp.197~210 (1985)
  6. Choi IJ, "An analysis of 2361 cases of renal biopsy in Korea", Yonsei Med J, 32, pp.9~15 (1991)
  7. 김기현, "신생검 증례에 의한 사구체 신질환의 분석", 대한내과학회지, 49, pp.674~682 (1995)
  8. 오윤규, "성인 사구체 신염", 대한장학회지, 15, pp.289~299 (1996)
  9. Chang JH, "Changing prevalence of glomerular diseases in Korean adults: a review of 20 years of experience", Nephrol Dial Transplant, 24, pp.2406~2410 (2009)
  10. 대한신장학회, "IgA 신병증 치료를 위한 다기관 공동 연구 보고서 (Protocol I): IgA 신병증의 예후요인 규명을 위한 후향적 다기관 공동 임상 연구" (1998), 의학문화사
  11. Koyama A, "Natural history and risk factors for immunoglobulin A nephropathy in Japan", Am J Kidney Dis, 29, pp.526~532 (1997)
  12. Fennessy M, "HLA-DQ gene polymorphism in primary IgA nephropathy in three European populations", Kidney Int, 49, pp.477~480 (1996)
  13. Yoshida H, "Role of the deletion polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy", J Clin Invest, 96, pp.2162~2169 (1995)
  14. 박미나, "IgA 신병증 환자에게 있어 ACE 유전자 다형성에 따른 Angiotensin receptor blocker의 치료 효과", The Korean Journal of Nephrology, 27(1), pp.13~19 (2008), 대한신장학회
  15. Liu ZH, "Interleukin-1 receptor antagonist allele: is it a genetic link between Henoch-Schoenlein nephritis and IgA nephropathy?", Kidney Int, 51, pp.1938~1942 (1997)
  16. Lim CS, "Association of C-509T and T869C polymorphisms of transforming growth factor-beta1 gene with susceptibility to and progression of IgA nephropathy", Clin Nephrol, 63, pp.61~67 (2005)
  17. Qin W, "Peripheral B lymphocyte beta1,3 -galactosyltransferase and chaperone expression in immunoglobulin A nephropathy", J Intern Med, 258, pp.467~477 (2005)
  18. Gharavi AG, "IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23", Nat Genet, 26, pp.354~357 (2000)
  19. Hsu SI, "Racial and genetic factors in IgA nephropathy", Semin Nephrol, 28, pp.48~57 (2008)
  20. van den Wall Bake AW, "Serum levels and in vitro production of IgA subclasses in patients with primary IgA nephropathy", Clin Exp Immunol, 74, pp.115~120 (1988)
  21. Jones CL, "Polymeric IgA and immune complex concentrations in IgA-related renal disease", Kidney Int, 38, pp.323~331 (1990)
  22. Long JA, "IgA deposits and acute glomerulonephritis in a patient with staphylococcal infection", Am J Kidney Dis, 48, pp.851~855 (2006)
  23. Suzuki S, "Haemophilus parainfluenzae antigen and antibody in renal biopsy samples and serum of patients with IgA nephropathy", Lancet, 343, pp.12~16 (1994)
  24. Coppo R, "Roccatello D. Dietary antigens and primary immunoglobulin A nephropathy", J Am Soc Nephrol, 2(10), pp.S173~S180 (1992)
  25. Emancipator SN, "Immunoregulatory factor in the pathogenesis of IgA nephropathy", Kidney Int, 38, pp.1216~1229 (1990)
  26. Suzuki Y, "Potential immunopathogenic role of the mucosa- bone marrow axis in IgA nephropathy: insights from animal models", Semin Nephrol, 28, pp.66~77 (2008)
  27. Mestecky J, "Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy", Contrib Nephrol, 104, pp.172~182 (1993)
  28. Hiki Y, "O-linked oligosaccharide on IgA1 hinge region in IgA nephropathy: fundamental study for precise structure and possible role", Contrib Nephrol, 111, pp.73~84 (1995)
  29. Moldoveanu Z, "Patients with IgA nephropathy have increased serum galactose deficient IgA1 levels", Kidney Int, 71, pp.1148~1154 (2007)
  30. Tomana M, "Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG", Kidney Int, 52, pp.509~516 (1997)
  31. Hiki Y, "Reactivity of glomerular and serum IgA1 to jacalin in IgA nephropathy", Nephron, 72, pp.429~435 (1996)
  32. Suzuki H, "Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity", J Clin Invest, 119, pp.1668~1677 (2009)
  33. Mathew TH, "Recurrence of disease following renal transplantation", Am J Kidney Dis, 12, pp.85~96 (1988)
  34. Cuevas X, "Disappearance of mesangial IgA deposits from the kidneys of two donors after transplantation", Transplant Proc, 19, pp.2208~2209 (1987)
  35. van den Wall Bake AW, "Serum IgA and the production of IgA by peripheral blood and bone marrow lymphocytes in patients with primary IgA nephropathy: evidence for the bone marrow as a source of mesangial IgA", Am J Kidney Dis, 12, pp.410~414 (1988)
  36. Lee TW, "Production of IL-2 and expression of IL-2 receptor in IgA nephropathy", Korean J Intern Med, 7, pp.31~39 (1992)
  37. Schena FP, "Immunogenetic aspects of primary IgA nephropathy", Kidney Int, 48, pp.1998~2013 (1995)
  38. Lai KN, "Increased mRNA encoding for transforming factor-beta in CD4+ cells from patients with IgA nephropathy", Kidney Int, 46, pp.862~868 (1994)
  39. Imasawa T, "Bone marrow transplantation attenuates murine IgA nephropathy: role of a stem cell disorder", Kidney Int, 56, pp.1809~1817 (1999)
  40. Suzuki H, "Th1 polarization in murine IgA nephropathy directed by bone marrow-derived cells", Kidney Int, 72, pp.319~327 (2007)
  41. Moura IC, "Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy", J Am Soc Nephrol, 16, pp.2667~2676 (2005)
  42. Cederholm B, "Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy", Proc Natl Acad Sci U S A, 85, pp.4865~4868 (1988)
  43. Wyatt RJ, "Julian BA. Activation of complement in IgA nephropathy", Am J Kidney Dis, 12, pp.437~442 (1988)
  44. Roos A, "Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease", J Am Soc Nephrol, 17, pp.1724~1734 (2006)
  45. Nagata M, "Macrophages in childhood IgA nephropathy", Kidney Int, 48, pp.527~535 (1995)
  46. de Caestecker MP, "Detection of abnormal peripheral blood mononuclear cell cytokine networks in human IgA nephropathy", Kidney Int, 44, pp.1298~1308 (1993)
  47. Yoshioka K, "In situ expression of cytokines in IgA nephritis", Kidney Int, 44, pp.825~833 (1993)
  48. Lim CS, "Clinicopathological correlation of intrarenal cytokines and chemokines in IgA nephropathy", Nephrology, 8, pp.21~27 (2003)
  49. Ihm C, "IgA aggregates stimulate monocyte chemotactic peptide-1 expression in human mesangial cells", Nephrology, 5, pp.99~103 (2000)
  50. Gomez-Guerrero C, "Interaction of mesangial cells with IgA and IgG immune complexes: a possible mechanism of glomerular injury in IgA nephropathy", Contrib Nephrol, 104, pp.127~137 (1993)
  51. Novak J, "IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells", Contrib Nephrol, 157, pp.134~138 (2007)
  52. Tam KY, "Macromolecular IgA1 taken from patients with familial IgA Nephropathy or their asymptomatic relatives have higher reactivity to mesangial cells in vitro", Kidney Int, 75, pp.1330~1339 (2009)
  53. Hricik DE, "Glomerulonephritis", N Engl J Med, 339, pp.888~899 (1998)
  54. 진규복, "IgA 신증의 장기 예후", The Korean Journal of Nephrology, 25(3), pp.365~374 (2006), 대한신장학회
  55. Berthoux FC, "Natural history of primary IgA nephropathy", Semin Nephrol, 28, pp.4~9 (2008)
  56. Barratt J, "Treatment of IgA nephropathy", Kidney Int, 69, pp.1934~1938 (2006)
  57. Reich HN, "Remission of proteinuria improves prognosis in IgA nephropathy", J Am Soc Nephrol, 18, pp.3177~3183 (2007)
  58. Shen P, "Natural history and prognostic factors of IgA nephropathy presented with isolated microscopic hematuria in Chinese patients", Nephron Clin Pract, 106, pp.c157~c161 (2007)
  59. Goto M, "A scoring system to predict renal outcome in IgA nephropathy: a nationwide 10-year prospective cohort study" (2009), Nephrol Dial Transplant
  60. Jennette JC, "The immunohistology of IgA nephropathy", Am J Kidney Dis, 12, pp.348~352 (1988)
  61. Lee SM, "IgA nephropathy: morphologic predictors of progressive renal disease", Hum Pathol, 13, pp.314~322 (1982)
  62. Haas M, "Histologic subclassification of IgA nephropathy: a clinicopathologic study of 244 cases", Am J Kidney Dis, 29, pp.829~842 (1997)
  63. Lee HS, "Histological grading of IgA nephropathy predicting renal outcome: revisiting H. S. Lee’s glomerular grading system", Nephrol Dial Transplant, 20, pp.342~348 (2005)
  64. Praga M, "Treatment of IgA nephropathy with ACE inhibitors: a randomized and controlled trial", J Am Soc Nephrol, 14, pp.1578~1583 (2003)
  65. Li PK, "Hong Kong study using valsartan in IgA nephropathy (HKVIN): a double-blind, randomized, placebo-controlled study", Am J Kidney Dis, 47, pp.751~760 (2006)
  66. Pozzi C, "Corticosteroid effectiveness in IgA nephropathy: long-term results of a randomized, controlled trial", J Am Soc Nephrol, 15, pp.157~163 (2004)
  67. Ballardie FW, "Controlled prospective trial of prednisolone and cytotoxics in progressive IgA nephropathy", J Am Soc Nephrol, 13, pp.142~148 (2002)
  68. "Southwest Pediatric Nephrology Study Group. Association of IgA nephropathy with steroid-responsive nephrotic syndrome", Am J Kidney Dis, 5, pp.157~164 (1985)
  69. Tumlin JA, "Clinical presentation, natural history, and treatment of crescentic proliferative IgA nephropathy", Semin Nephrol, 24, pp.256~268 (2004)
  70. Donadio JV Jr, "A controlled trial of fish oil in IgA nephropathy", N Engl J Med, 331, pp.1194~1199 (1994)

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