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Micro-Biopsy Forceps in the Assessment of Peritoneal Carcinomatosis: A Possible New Indication?

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초록

Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it ischaracterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled outbefore any invasive treatment is administered. A new through-the-needle micro-biopsy forceps (MF) was recently introduced thatpermits micro-histology cores. In this case series, we evaluated the feasibility of MF in the assessment of PC to complete patientdiagnostic work-ups. Five consecutive patients referred for endoscopic ultrasound staging were sampled using MF. Sampling wasfeasible in all patients with a technical success of 100%. No adverse events were reported in any cases. This technique was feasibleand safe with a technical success rate of 100%. It permitted sampling of peritoneal irregularity, obtained high-quality tissue fragmentsin all cases, and enabled an additional assessment, i.e., immunohistochemical staining.

Abstract

Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it ischaracterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled outbefore any invasive treatment is administered. A new through-the-needle micro-biopsy forceps (MF) was recently introduced thatpermits micro-histology cores. In this case series, we evaluated the feasibility of MF in the assessment of PC to complete patientdiagnostic work-ups. Five consecutive patients referred for endoscopic ultrasound staging were sampled using MF. Sampling wasfeasible in all patients with a technical success of 100%. No adverse events were reported in any cases. This technique was feasibleand safe with a technical success rate of 100%. It permitted sampling of peritoneal irregularity, obtained high-quality tissue fragmentsin all cases, and enabled an additional assessment, i.e., immunohistochemical staining.

참고문헌 (20)

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