내시경 유두절제술로 제거한 거대 십이지장 주유두의 신경내분비종양
A Large Neuroendocrine Tumor of the Major Duodenal Papilla Removed by Endoscopic Papillectomy
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Neuroendocrine tumors (NET) of the major duodenal papilla are rare and the natural history of this disease is not clear. Weexperienced a case in a 31-year-old male. Duodenoscopy revealed an enlarged major duodenal papilla with central umbilication andnodularity. Endoscopic ultrasonography (EUS) demonstrated a 3-cm hypoechoic mass that was confined to the submucosa. Abiopsy led to the diagnosis of a grade 1 NET. The patient refused surgery, so we performed an endoscopic papillectomy. The tumorwas removed completely. The resected specimen confirmed the diagnosis of a well-differentiated NET and all resection marginswere negative. Surgical resection is currently considered to be the gold standard for the treatment of a large NET of the majorduodenal papilla; however, endoscopic resection is a possible treatment modality for patients at high surgical risk or who arereluctant to undergo surgery.
Abstract
Neuroendocrine tumors (NET) of the major duodenal papilla are rare and the natural history of this disease is not clear. Weexperienced a case in a 31-year-old male. Duodenoscopy revealed an enlarged major duodenal papilla with central umbilication andnodularity. Endoscopic ultrasonography (EUS) demonstrated a 3-cm hypoechoic mass that was confined to the submucosa. Abiopsy led to the diagnosis of a grade 1 NET. The patient refused surgery, so we performed an endoscopic papillectomy. The tumorwas removed completely. The resected specimen confirmed the diagnosis of a well-differentiated NET and all resection marginswere negative. Surgical resection is currently considered to be the gold standard for the treatment of a large NET of the majorduodenal papilla; however, endoscopic resection is a possible treatment modality for patients at high surgical risk or who arereluctant to undergo surgery.
참고문헌 (10)
- Jayant M, "Neuroendocrine tumors of the ampulla of Vater: presentation, pathology and prognosis", JOP, 13, pp.263~267 (2012)
- Clements WM, "Ampullary carcinoid tumors: rationale for an aggressive surgical approach", J Gastrointest Surg, 7, pp.773~776 (2003)
- Hatzitheoklitos E, "Carcinoid of the ampulla of Vater: clinical characteristics and morphologic features", Cancer, 73, pp.1580~1588 (1994)
- Hartel M, "Carcinoid of the ampulla of Vater", J Gastroenterol Hepatol, 20, pp.676~681 (2005)
- Irani S, "Papillectomy for ampullary neoplasm: results of a single referral center over a 10-year period", Gastrointest Endosc, 70, pp.923~932 (2009)
- Strosberg JR, "Prognostic validity of the American Joint Committee on Cancer staging classification for midgut neuroendocrine tumors", J Clin Oncol, 31, pp.420~425 (2013)
- Gilani N, "Endoscopic resection of an ampullary carcinoid presenting with upper gastrointestinal bleeding: a case report and review of the literature", World J Gastroenterol, 13, pp.1268~1270 (2007)
- Pyun DK, "A carcinoid tumor of the ampulla of Vater treated by endoscopic snare papillectomy", Korean J Intern Med, 19, pp.257~260 (2004)
- Fukatsu H, "Periampullary carcinoid tumor", Endoscopy, 39(1), pp.E49~50 (2007)
- Han J, "Endoscopic papillectomy for adenomas of the major duodenal papilla (with video)", Gastrointest Endosc, 63, pp.292~301 (2006)