강직성 척추염 환자에서 발생한 갑상선자극호르몬(TSH) 분비 뇌하수체 선종 1예
A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
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초록
저자들은 강직성 척추염을 진단받고 외래에서 추적관찰중인 환자에서 동반된 갑상선자극호르몬 분비 뇌하수체 선종을 TRH 자극검사, 갑상선자극호르몬 α‐아단위 측정 및 자기공명영상으로 진단하고 수술로 치료하여서 호전된 드문증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 두질환과의 상호 연관성에 대해서는 추가적인 연구가 필요할것으로 판단된다.
Abstract
A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH α-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.
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