유루증을 보이는 프로락틴, 성장호르몬 혼합분비 뇌하수체 미세선종 1예
A case of mixed prolactin and growth hormone-secreting pituitary microadenoma presenting galactorrhea
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유루증을 동반한 경미한 말단비대증 환자에서 뇌하수 체 미세선종의 수술적 절제 후, 뇌하수체 기능저하증 없 이 호전되어, 건강하게 외래 추적 경과 관찰하게 된 프 로락틴-성장호르몬 혼합 분비성 뇌하수체 미세선종 1예 를 보고하는 바이다.
Abstract
We report a case of galactorrhea with acromegaly from the mixed prolactin and GH secreting pituitary microadenoma managed with a successful surgical complete removal. A 31-year-old woman visited our hospital complaining galactorrhea for more than 6 months after delivery. The physical findings of the patient were a prominent galactorrhea and mild acromegalic features of face and extremities. The laboratory findings of hematology and blood chemistry were normal. In addition, the basal levels of prolactin and GH were slightly elevated. The thyroid is in euthyroid state. The results of the combined anterior pituitary hormone-stimulation tests were that the prolactin and GH responses were stimulated exaggeratedly and the other hormonal ones were normal responses. The oral glucose loading test for acromegaly revealed non-responder results. The sellar MRI showed the 6×5 mm-sized pituitary microadenoma. She was operated for surgical removal of the lesions of which the immunohistochemistry findings were consistent with the positive findings for both prolactin and GH. She discharged without post-operative complication and has done well with normalized hormonal levels at outpatient department.(Korean J Med 64:690-694, 2003)