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Inaccuracy of Intraocular Lens Power Prediction for Cataract Surgery in Angle-Closure Glaucoma

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초록

Purpose: To assess the accuracy of intraocular lens (IOL) power predictions for cataract surgery in eyes with primary angleclosure glaucoma (ACG). Because of shifting of the capsular bag apparatus and shortening of the axial length, preoperative calculation of IOL power may be inaccurate for eyes with ACG. Materials and Methods: This retrospective comparative case series comprised of 42 eyes from 42 patients with primary ACG and 45 eyes from 45 subjects with normal open-angles undergoing uneventful cataract surgery. Anterior segment biometry including anterior chamber depth, lens thickness, and axial length were compared. Using the SRK-Ⅱ formula, the powers of the implanted IOL and the actual postoperative spherical equivalent (SE) refractive errors were compared between the two groups. Also, the absolute values of differences between predicted and residual SE refractive errors were also analyzed for each group. Results: In ACG patients, anterior chamber depth and axial length were shorter and the lens was thicker than normal controls (all p < 0.001). Even though residual SE refractive error was not significantly different (p = 0.290), the absolute value of the difference between predicted and residual SE refractive error was 0.64 ± 0.50 diopters in AGC patients and 0.39 ± 0.36 diopters in control subjects (p = 0.012). The number of eyes that resulted in inaccurate IOL power predictions of more than 0.5 diopters were 21 (50.00%) in the ACG group, but only 12 (26.67%) in the control group (p = 0.043). Conclusion: IOL power predictions for cataract surgery in ACG patients can be inaccurate, and it may be associated with their unique anterior segment anatomy.

Abstract

Purpose: To assess the accuracy of intraocular lens (IOL) power predictions for cataract surgery in eyes with primary angleclosure glaucoma (ACG). Because of shifting of the capsular bag apparatus and shortening of the axial length, preoperative calculation of IOL power may be inaccurate for eyes with ACG. Materials and Methods: This retrospective comparative case series comprised of 42 eyes from 42 patients with primary ACG and 45 eyes from 45 subjects with normal open-angles undergoing uneventful cataract surgery. Anterior segment biometry including anterior chamber depth, lens thickness, and axial length were compared. Using the SRK-Ⅱ formula, the powers of the implanted IOL and the actual postoperative spherical equivalent (SE) refractive errors were compared between the two groups. Also, the absolute values of differences between predicted and residual SE refractive errors were also analyzed for each group. Results: In ACG patients, anterior chamber depth and axial length were shorter and the lens was thicker than normal controls (all p < 0.001). Even though residual SE refractive error was not significantly different (p = 0.290), the absolute value of the difference between predicted and residual SE refractive error was 0.64 ± 0.50 diopters in AGC patients and 0.39 ± 0.36 diopters in control subjects (p = 0.012). The number of eyes that resulted in inaccurate IOL power predictions of more than 0.5 diopters were 21 (50.00%) in the ACG group, but only 12 (26.67%) in the control group (p = 0.043). Conclusion: IOL power predictions for cataract surgery in ACG patients can be inaccurate, and it may be associated with their unique anterior segment anatomy.

참고문헌 (8)

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  2. Hayashi K, "Changes in anterior chamber angle width and depth after intraocular lens implantation in eyes with glaucoma", Ophthalmology, 107, pp.698~703 (2000)
  3. Nonaka A, "Angle widening and alteration of ciliary process configuration after cataract surgery for primary angle closure", Ophthalmology, 113, pp.437~441 (2006)
  4. Francis BA, "Changes in axial length following trabeculectomy and glaucoma drainage device surgery", Br J Ophthalmol, 89, pp.17~20 (2005)
  5. Law SK, "Effects of combined cataract surgery and trabeculectomy with mitomycin C on ocular dimensions", Br J Ophthalmol, 89, pp.1021~1025 (2005)
  6. Lowe RF, "Aetiology of the anatomical basis for primary angle-closure glaucoma. Biometrical comparisons between normal eyes and eyes with primary angle-closure glaucoma", Br J Ophthalmol, 54, pp.161~169 (1970)
  7. Markowitz SN, "Angle-closure glaucoma: relation between lens thickness, anterior chamber depth and age", Can J Ophthalmol, 19, pp.300~302 (1984)
  8. Marchini G, "Ultrasound biomicroscopic and conventional ultrasonographic study of ocular dimensions in primary angle-closure glaucoma", Ophthalmology, 105, pp.2091~2098 (1998)

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