Changes in Abdominal Obesity Affect the Risk of Metachronous Advanced Colorectal Neoplasia Development after Polypectomy
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: The impact of changes in body mass index and waist circumference on the development of metachronous colorectal neoplasia (CRN) after polypectomy has rarely been examined. We evaluated the association between changes in overall/abdominal obesity and metachronous CRN risk. Materials and Methods: We studied patients who underwent ≥1 adenoma removal and surveillance colonoscopy. Patients were classified into the following four groups based on the changes in overall obesity from index to follow-up colonoscopy: non-obesity persisted (group 1), obesity to non-obesity (group 2), non-obesity to obesity (group 3), and obesity persisted (group 4). Patients were also divided into another four groups based on similar changes in abdominal obesity (groups 5–8). Results: The number of patients in groups 1, 2, 3, and 4 was 5074, 457, 643, and 3538, respectively, and that in groups 5, 6, 7, and 8 was 4229, 538, 656, and 2189, respectively. Group 4 had a significantly higher risk of metachronous CRN compared to groups 1 and 2. However, metachronous advanced CRN (ACRN) risk was not different among groups 1, 2, 3, and 4. Metachronous CRN risk in group 8 (abdominal obesity persisted) was higher than that in groups 5 (non-abdominal obesity persisted) and 7 (non-abdominal obesity to abdominal obesity), and tended to be higher than that in group 6 (abdominal obesity to non-abdominal obesity). Additionally, group 8 had a significantly higher risk of metachronous ACRN compared to groups 5, 6, and 7. Conclusion: Changes in obesity affected the metachronous CRN risk. In particular, changes in abdominal obesity affected the metachronous ACRN risk.
Abstract
Purpose: The impact of changes in body mass index and waist circumference on the development of metachronous colorectal neoplasia (CRN) after polypectomy has rarely been examined. We evaluated the association between changes in overall/abdominal obesity and metachronous CRN risk. Materials and Methods: We studied patients who underwent ≥1 adenoma removal and surveillance colonoscopy. Patients were classified into the following four groups based on the changes in overall obesity from index to follow-up colonoscopy: non-obesity persisted (group 1), obesity to non-obesity (group 2), non-obesity to obesity (group 3), and obesity persisted (group 4). Patients were also divided into another four groups based on similar changes in abdominal obesity (groups 5–8). Results: The number of patients in groups 1, 2, 3, and 4 was 5074, 457, 643, and 3538, respectively, and that in groups 5, 6, 7, and 8 was 4229, 538, 656, and 2189, respectively. Group 4 had a significantly higher risk of metachronous CRN compared to groups 1 and 2. However, metachronous advanced CRN (ACRN) risk was not different among groups 1, 2, 3, and 4. Metachronous CRN risk in group 8 (abdominal obesity persisted) was higher than that in groups 5 (non-abdominal obesity persisted) and 7 (non-abdominal obesity to abdominal obesity), and tended to be higher than that in group 6 (abdominal obesity to non-abdominal obesity). Additionally, group 8 had a significantly higher risk of metachronous ACRN compared to groups 5, 6, and 7. Conclusion: Changes in obesity affected the metachronous CRN risk. In particular, changes in abdominal obesity affected the metachronous ACRN risk.
참고문헌 (24)
- Ma Y, "Obesity and risk of colorectal cancer : a systematic review of prospective studies", PLoS One, 8, pp.e53916~ (2013)
- Okabayashi K, "Body mass index category as a risk factor for colorectal adenomas : a systematic review and meta-analysis", Am J Gastroenterol, 107, pp.1175~1185 (2012)
- Lu Y, "Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma : a large prospective cohort study in Norway", Epidemiology, 27, pp.423~432 (2016)
- Li H, "Body weight, fat distribution and colorectal cancer risk: a report from cohort studies of 134255 Chinese men and women", Int J Obes(Lond), 37, pp.783~789 (2013)
- Song M, "Long-term status and change of body fat distribution, and risk of colorectal cancer : a prospective cohort study", Int J Epidemiol, 45, pp.871~883 (2016)
- Dong Y, "Abdominal obesity and colorectal cancer risk : systematic review and meta-analysis of prospective studies", Biosci Rep, 37, pp.BSR20170945~ (2017)
- Kim NH, "Abdominal obesity is more predictive of advanced colorectal neoplasia risk than overall obesity in men : a cross-sectional study", J Clin Gastroenterol, 53, pp.e284~e290 (2019)
- Hong S, "Abdominal obesity and the risk of colorectal adenoma : a meta-analysis of observational studies", Eur J Cancer Prev, 21, pp.523~531 (2012)
- Ashbeck EL, "Components of metabolic syndrome and metachronous colorectal neoplasia", Cancer Epidemiol Biomarkers Prev, 18, pp.1134~1143 (2009)
- Kim B, "Visceral adipose tissue volume and the occurrence of colorectal adenoma in follow-up colonoscopy for screening and surveillance", Nutr Cancer, 69, pp.739~745 (2017)
- Kim TJ, "Obesity-related parameters and colorectal adenoma development", J Gastroenterol, 52, pp.1221~1229 (2017)
- Jacobs ET, "Association between body mass index and colorectal neoplasia at follow-up colonoscopy : a pooling study", Am J Epidemiol, 169, pp.657~666 (2009)
- Jung YS, "Effect of cotinine-verified change in smoking status on risk of metachronous colorectal neoplasia after polypectomy", Clin Gastroenterol Hepatol, 18, pp.163~170 (2020)
- Soweid AM, "A randomized single-blind trial of standard diet versus fiber-free diet with polyethylene glycol electrolyte solution for colonoscopy preparation", Endoscopy, 42, pp.633~638 (2010)
- Wen CP, "Are Asians at greater mortality risks for being overweight than Caucasians? Redefining obesity for Asians", Public Health Nutr, 12, pp.497~506 (2009)
- Alberti KG, "Harmonizing the metabolic syndrome : a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation;International Atherosclerosis Society; and International Association for the Study of Obesity", Circulation, 120, pp.1640~1645 (2009)
- Lieberman DA, "Guidelines for colonoscopy surveillance after screening and polypectomy : a consensus update by the US Multi-Society Task Force on Colorectal Cancer", Gastroenterology, 143, pp.844~857 (2012)
- Laiyemo AO, "Obesity, weight change, and risk of adenoma recurrence : a prospective trial", Endoscopy, 44, pp.813~818 (2012)
- Yamaji Y, "The effect of body weight reduction on the incidence of colorectal adenoma", Am J Gastroenterol, 103, pp.2061~2067 (2008)
- Jung YS, "Weight change and obesity are associated with a risk of adenoma recurrence", Dig Dis Sci, 61, pp.2694~2703 (2016)
- Im JP, "Visceral obesity as a risk factor for colorectal adenoma occurrence in surveillance colonoscopy", Gastrointest Endosc, 88, pp.119~127 (2018)
- Neeland IJ, "Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults", Obesity(Silver Spring), 21, pp.E439~E447 (2013)
- Freedland ES, "Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a review", Nutr Metab(Lond), 1, pp.12~ (2004)
- In Sub Jung, "Association of visceral adiposity and insulin resistance with colorectal adenoma and colorectal cancer", Intestinal research, 17(3), pp.404~412 (2019), 대한장연구학회[DOI]