국내 일부지역의 식도암 발생 위험요인과 관련된 요인
Factors Related to the Risk Factors of Esophageal Cancer Incidence of Local Area in Korea
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본 연구는 국내 일부지역의 식도암 발생 위험요인과 관련된 요인을 규명하기 위해 수행하였다. 자료는 2015년 12월 1일부터 2016년 1월 31일까지 서울지역에 소재한 종합병원 내과에 내원한 환자군 76명, 대조군 76명을 대상으로 시행하였다. 연구대상자의 일반적인 특성과 의료행태와 관련된 요인은 Chi-square test를 시행하였다. 식도암 위험요인간의 교치비를 구하기 위해 multiple logistic regression analysis를 사용하였다. 연구결과는 다음과 같다. 첫째, 가족력을 보면 가족력이 있는 경우 환자군이 60.6%로 대조군의 39.4% 보다 유의하게 높게 나타났다(X2=1.67, p<.05). 둘째, 고혈압여부는 고혈압이 있는 경우 환자군은 67.3% 대조군은 32.7%로 환자군이 대조군보다 유의하게 높은 분포를 보였다(X2=2.96, p<.05). 셋째, 성별은 여성에 비해 남성에서 식도암의 위험요인이 4.28배 유의하게 높게 나타났다(OR=3.12, 95% Cl=1.57-8.64) 넷째, 남성, 현재흡연을 할수록, 당뇨병과 복부비만이 있는 경우 식도암 위험요인이 유의하게 나타났다(p<.05). 이러한 결과를 토대로 식도암의 효과적인 예방은 교육 및 검진이 요구된다고 본다.
Abstract
This study was attempted to identify the factors influencing on esophageal cancer incidence of local area in Korea. A total of 76 incident cases of esophageal cancer admitted to the department of internal medicine in a general hospital form December 1, 2015 to January 31, 2016 were compared with 76 matched controls admitted to same hospital in same period. Factors associated with general characteristics and medical behaviors were performed using Chi-square test. Odds ratio between risk factors of esophageal cancer were analyzed using multiple logistic regression analysis, Major findings are as follows. Firstly, for family history, case groups who have family history were significantly higher than control group(X2=1.67, p<.05). Secondly, case group who have hypertension were significantly higher than control group(X2=2.96, p<.05). Thirdly, for gender, men were significantly higher 3.12 times than women in risk factor of esophageal cancer(OR=3.12, 95% Cl=1.57-8.64). Fourthly, through the logisticregression, it were statistically associated factors with esophageal cancer in subjects who were abdominal obesity, diabetes mellitus, current smoking(p<.05). Based on this study, for effective prevention of the esophageal cancer, it is required to education and screening examination.
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