질 후원개에 발생한 원발성 악성 흑색종 1예
A Case of Primary Malignant Melanoma of Posterior Vaginal Fornix
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초록
원발성 질 악성 흑색종은 여성 10만 명당 0.026명 정도 발생하는 매우 드문 질환이며 치료법에 대한 의견이 다양하게 제시되고 있으나 예후는 매우 불량한 것으로 알려져 있다. 일반적으로 흑색종은 방사선치료에 저항성을 보이는 종양으로 여겨지지만 최근 고선량의 분할조사선량을 이용한 방사선치료가 원발성이나 전이성 흑색종 병변에 높은 반응율을 보인다는 보고가 있다. 저자들은 최근에 세기조절 방사선으로 치료한 원발성 질 악성 흑색종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
Abstract
Primary malignant melanoma of the vagina is a very rare disease with incidence of 0.026 per 100,000 women. The opinion of several types of treatment is suggested but the prognosis is extremely poor. Although malignant melanoma is generally regarded as a radioresistant tumor, recent reports show that definitive irradiation with high-dose fractionation regimen demonstrates high response rates in primary and metastatic lesions. A case of primary malignant melanoma of the vagina which was treated with intensity-modulated radiation therapy is presented with a brief review of concerned literature.
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