난소의 양성 기형종에서 유래된 원발성 악성 흑색종 1예
Primary malignant melanoma arising from ovarian mature cystic teratoma: A case report and literature review
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초록
난소의 양성 기형종에서 유래된 원발성 악성 흑색종은 매우 드문 질환이다. 대략 31개의 증례만이 보고된 바 있고 대개는 폐경된 여성에서 일측성 기형종의 악성 변환으로 나타난다. 최근 저자들은 71세 환자에서 양성 기형종에서 유래된 원발성 악성 흑색종을 경험하였는데, 악성 흑색종의 진단은 S-100 단백질과 HMB 45 양성반응으로 확진되었다. 이에 간단한 문헌고찰과 함께 보고하는 바이다.
Abstract
Primary malignant melanoma arising from the ovarian mature cystic teratoma is extremely rare, with only 31 cases have been described in the literature. It is one of the rarest forms of malignant transformation of ovarian mature cystic teratoma and usually develops unilaterally after menopause. Recently, we experienced a case of primary malignant melanoma arising from ovarian mature cystic teratoma in 71-year-old woman. The diagnosis was confirmed by positive immunohistochemical results of S-100 protein and HMB 45. Here we report the rare case with review of literature.
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