A case of extremely early cervical adenocarcinoma diagnosed only by endocervical curettage with macroscopic pelvic lymph node metastases
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Microinvasive adenocarcinoma is not as well studied as microinvasive squamous cell carcinoma because diagnosis ofadenocarcinoma cannot be ascertained for early invasive lesions. However, most clinicians consider a depth of invasionof 3 mm without lympho-vascular space invasion as the maximum limit for conservative management. Microinvasivecervical adenocarcinoma is characterized by a rare incidence of lymph node metastasis and very good prognosis. We describe a 62-year-old patient with an extremely early cervical adenocarcinoma which was detected only byendocervical curettage. However, she had multiple macroscopic pelvic node metastases. Clinicians should considerthe probability of lymph node metastasis, although management of stage IA1 cervical adenocarcinoma may still beconservative.
Abstract
Microinvasive adenocarcinoma is not as well studied as microinvasive squamous cell carcinoma because diagnosis ofadenocarcinoma cannot be ascertained for early invasive lesions. However, most clinicians consider a depth of invasionof 3 mm without lympho-vascular space invasion as the maximum limit for conservative management. Microinvasivecervical adenocarcinoma is characterized by a rare incidence of lymph node metastasis and very good prognosis. We describe a 62-year-old patient with an extremely early cervical adenocarcinoma which was detected only byendocervical curettage. However, she had multiple macroscopic pelvic node metastases. Clinicians should considerthe probability of lymph node metastasis, although management of stage IA1 cervical adenocarcinoma may still beconservative.
참고문헌 (11)
- Sherman ME, "Mortality trends for cervical squamous and adenocarcinoma in the United States. Relation to incidence and survival", Cancer, 103, pp.1258~1264 (2005)
- Pecorelli S, "Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium", Int J Gynaecol Obstet, 105, pp.103~104 (2009)
- Baalbergen A, "Conservative therapy in microinvasive adenocarcinoma of the uterine cervix is justified : an analysis of 59 cases and a review of the literature", Int J Gynecol Cancer, 21, pp.1640~1645 (2011)
- Bean LM, "Survival of women with microinvasive adenocarcinoma of the cervix is not improved by radical surgery", Am J Obstet Gynecol, 217, pp.332~ (2017)[DOI]
- Reynolds EA, "Analysis of outcomes of microinvasive adenocarcinoma of the uterine cervix by treatment type", Obstet Gynecol, 116, pp.1150~1157 (2010)
- Nagarsheth NP, "Bilateral pelvic lymph node metastases in a case of FIGO stage IA(1)adenocarcinoma of the cervix", Gynecol Oncol, 77, pp.467~470 (2000)
- Galic V, "Prognostic significance of adenocarcinoma histology in women with cervical cancer", Gynecol Oncol, 125, pp.287~291 (2012)
- Lee YY, "A comparison of pure adenocarcinoma and squamous cell carcinoma of the cervix after radical hysterectomy in stage IB–IIA", Gynecol Oncol, 120, pp.439~443 (2011)
- Im SS, "Early stage cervical cancers containing human papillomavirus type 18 DNA have more nodal metastasis and deeper stromal invasion", Clin Cancer Res, 9, pp.4145~4150 (2003)
- Akladios C, "Reliability of endocervical curettage in the diagnosis of high-grade cervical neoplasia and cervical cancer in selected patients", Anticancer Res, 35, pp.4183~4189 (2015)
- Holschneider CH, "Berek & Novak’s gynecology", pp.135~137 (2014), Lippincott Williams & Wilkins