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Minimal Deviation Endometrioid Adenocarcinoma of the Uterine Cervix - A Case Report -

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초록

We describe here a case of minimal deviation endometrioid adenocarcinoma (MDEA) of the uterine cervix that was initially suspected according to the abnormal cytologic findings in a 39-year-old woman. The Papanicolaou (pap) smear showed many neoplastic glandular cells in monolayered sheets, rosettes, and clusters with palisading and feathering borders. The tumor cells had oval, hyperchromatic nuclei, with chromatin clumping and small nucleoli. Histologic examination disclosed endometrial-type glands with a bland, isolated, mainly rounded appearance and these glands were widely scattered deep into the cervical stroma with only scant stromal reaction. An association of MDEA with tubo-endometrioid metaplasia or cervical endometriosis has been suggested by identifying the tubo-endometrioid glands in the vicinity of the MDEA.

Abstract

We describe here a case of minimal deviation endometrioid adenocarcinoma (MDEA) of the uterine cervix that was initially suspected according to the abnormal cytologic findings in a 39-year-old woman. The Papanicolaou (pap) smear showed many neoplastic glandular cells in monolayered sheets, rosettes, and clusters with palisading and feathering borders. The tumor cells had oval, hyperchromatic nuclei, with chromatin clumping and small nucleoli. Histologic examination disclosed endometrial-type glands with a bland, isolated, mainly rounded appearance and these glands were widely scattered deep into the cervical stroma with only scant stromal reaction. An association of MDEA with tubo-endometrioid metaplasia or cervical endometriosis has been suggested by identifying the tubo-endometrioid glands in the vicinity of the MDEA.

참고문헌 (7)

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  2. Kaminski PF, "Minimal deviation carcinoma (adenoma malignum) of the cervix", Int J Gynecol Pathol, 2, pp.141~152 (1983)
  3. Rhahilly MA, "Minimal deviation endometrioid adenocarcinoma of the uterine cervix: a clinicopathological and immunohistochemical study of the two cases", Histopathology, 20, pp.351~354 (1992)
  4. Young RH, "Minimal deviation endometrioid adenocarcinoma of the uterine cervix. A report of five cases of a distinctive neoplasm that may be misinterpreted as benign", Am J Surg Pathol, 17, pp.660~665 (1993)
  5. Odashiro AN, "Minimal deviation endometrioid adenocarcinoma of the cervix: report of three cases with exfoliative cytology", Diagn Cytopathol, 34, pp.119~123 (2006)
  6. Ismail SM, "Cone biopsy causes cervical endometriosis and tubo-endometrioid metaplasia", Histopathology, 18, pp.107~114 (1991)
  7. Covell JL, "Epithelial abnormalities: glandular. In: Solomon D and Nayar R, eds. The Bethesda System for reporting cervical cytology. 2nd ed", pp.123~156 (2004), Springer

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