Fatigue Severity and Factors Associated with High Fatigue Levels in Korean Patients with Inflammatory Bowel Disease
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Background/Aims: Many patients with inflammatory boweldisease (IBD) often complain of fatigue. To date, only a fewstudies in Western countries have focused on fatigue relatedto IBD, and fatigue has never been specifically studied inAsian IBD patients. The aim of the present study was to investigatethe fatigue level and fatigue-related factors amongKorean IBD patients. Methods: Patients in remission or withmild to moderate IBD were included. Fatigue was assessedusing the Functional Assessment of Chronic Illness Therapy-Fatigue and the Brief Fatigue Inventory. Correspondinghealthy controls (HCs) also completed both fatigue questionnaires. Results: Sixty patients with Crohn disease and 68patients with ulcerative colitis (UC) were eligible for analysis. The comparison group consisted of 92 HCs. Comparedwith the HCs, both IBD groups were associated with greaterlevels of fatigue (p<0.001). Factors influencing the fatiguescore in UC patients included anemia and a high erythrocytesedimentation rate (ESR). Conclusions: Greater levelsof fatigue were detected in Korean IBD patients comparedwith HCs. Anemia and ESR were determinants of fatigue inUC patients. Physicians need to be aware of fatigue as oneof the important symptoms of IBD to better understand theimpact of fatigue on health-related quality of life.
Abstract
Background/Aims: Many patients with inflammatory boweldisease (IBD) often complain of fatigue. To date, only a fewstudies in Western countries have focused on fatigue relatedto IBD, and fatigue has never been specifically studied inAsian IBD patients. The aim of the present study was to investigatethe fatigue level and fatigue-related factors amongKorean IBD patients. Methods: Patients in remission or withmild to moderate IBD were included. Fatigue was assessedusing the Functional Assessment of Chronic Illness Therapy-Fatigue and the Brief Fatigue Inventory. Correspondinghealthy controls (HCs) also completed both fatigue questionnaires. Results: Sixty patients with Crohn disease and 68patients with ulcerative colitis (UC) were eligible for analysis. The comparison group consisted of 92 HCs. Comparedwith the HCs, both IBD groups were associated with greaterlevels of fatigue (p<0.001). Factors influencing the fatiguescore in UC patients included anemia and a high erythrocytesedimentation rate (ESR). Conclusions: Greater levelsof fatigue were detected in Korean IBD patients comparedwith HCs. Anemia and ESR were determinants of fatigue inUC patients. Physicians need to be aware of fatigue as oneof the important symptoms of IBD to better understand theimpact of fatigue on health-related quality of life.
참고문헌 (25)
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