The Risk Factors and Quality of Life in Patients with Overlapping Functional Dyspepsia or Peptic Ulcer Disease with Gastroesophageal Reflux Disease
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Background/Aims: Gastroesophageal reflux disease(GERD), functional dyspepsia (FD), and peptic ulcer disease(PUD) impact the daily lives of affected individuals. The aimof this study was to compare the risk factors and impacts onlife quality of overlapping FD or PUD in patients with GERD. Methods: Data from patients diagnosed with GERD werecollected between January and November 2009. FD wasdefined using the Rome III diagnostic criteria. The overlappingGERD-FD or GERD-PUD groups were classified as concomitantGERD and FD or peptic ulcers. The characteristicsof these individuals were analyzed. Results: There were 63,48, and 60 patients in the GERD only, overlapping GERD-FD,and overlapping GERD-PUD groups, respectively. Significantlyyounger age, female gender, lower body weight and bodymass index, and higher rates of tea consumption were notedin the GERD-FD group. Patients in the GERD-FD group exhibitedthe lowest quality of life scores, both with respect tophysical and mental health, on the Short Form 36 domains. Conclusions: Patients with concomitant GERD and FD weremore likely to be younger and female. Overlapping GERD andFD had the worst impact on the quality of life of the affectedindividuals.
Abstract
Background/Aims: Gastroesophageal reflux disease(GERD), functional dyspepsia (FD), and peptic ulcer disease(PUD) impact the daily lives of affected individuals. The aimof this study was to compare the risk factors and impacts onlife quality of overlapping FD or PUD in patients with GERD. Methods: Data from patients diagnosed with GERD werecollected between January and November 2009. FD wasdefined using the Rome III diagnostic criteria. The overlappingGERD-FD or GERD-PUD groups were classified as concomitantGERD and FD or peptic ulcers. The characteristicsof these individuals were analyzed. Results: There were 63,48, and 60 patients in the GERD only, overlapping GERD-FD,and overlapping GERD-PUD groups, respectively. Significantlyyounger age, female gender, lower body weight and bodymass index, and higher rates of tea consumption were notedin the GERD-FD group. Patients in the GERD-FD group exhibitedthe lowest quality of life scores, both with respect tophysical and mental health, on the Short Form 36 domains. Conclusions: Patients with concomitant GERD and FD weremore likely to be younger and female. Overlapping GERD andFD had the worst impact on the quality of life of the affectedindividuals.
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