Breast Cancer Metastasis to the Stomach Resembling Early Gastric Cancer
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Breast cancer metastases to the stomach are infrequent, with an estimated incidence rate of approximately 0.3%. Gastric metastases usually are derived from lobular rather than from ductal breast cancer. The most frequent type of a breast cancer metastasis as seen on endoscopy to the stomach is linitis plastica; features of a metastatic lesion that resemble early gastric cancer (EGC) are extremely rare. In this report, we present a case of a breast cancer metastasis to the stomach from an infiltrating ductal carcinoma (IDC) of the breast in a 48-year-old woman. The patient had undergone a left modified radical mastectomy with axillary dissection nine years prior. A gastric endoscopy performed for evaluation of nausea and anorexia showed the presence of a slightly elevated mucosal lesion in the cardia, suggestive of a type IIa EGC. A histological examination revealed nests of a carcinoma in the subepithelial lymphatics, and immunohistochemical staining for estrogen receptor was positive. This is an extremely rare case with features of type IIa EGC, but the lesion was finally identified as a cancer metastasis to the cardia of the stomach from an IDC of the breast.
Abstract
Breast cancer metastases to the stomach are infrequent, with an estimated incidence rate of approximately 0.3%. Gastric metastases usually are derived from lobular rather than from ductal breast cancer. The most frequent type of a breast cancer metastasis as seen on endoscopy to the stomach is linitis plastica; features of a metastatic lesion that resemble early gastric cancer (EGC) are extremely rare. In this report, we present a case of a breast cancer metastasis to the stomach from an infiltrating ductal carcinoma (IDC) of the breast in a 48-year-old woman. The patient had undergone a left modified radical mastectomy with axillary dissection nine years prior. A gastric endoscopy performed for evaluation of nausea and anorexia showed the presence of a slightly elevated mucosal lesion in the cardia, suggestive of a type IIa EGC. A histological examination revealed nests of a carcinoma in the subepithelial lymphatics, and immunohistochemical staining for estrogen receptor was positive. This is an extremely rare case with features of type IIa EGC, but the lesion was finally identified as a cancer metastasis to the cardia of the stomach from an IDC of the breast.
참고문헌 (15)
- Taal BG, "Thespectrum of gastrointestinal metastases of breast carcinoma", I.Stomach. Gastrointest Endosc, 38, pp.130~5 (1992)
- McLemore EC, "Breast cancer: presentation and interventionin women with gastrointestinal metastasis and carcinomatosis", Ann Surg Oncol, 12, pp.886~94 (2005)
- Taal BG, "Clinical presentation, endoscopicfeatures, and treatment of gastric metastases from breast carcinoma", Cancer, 89, pp.2214~21 (2000)
- Dumoulin FL, "Breast cancer metastasis to thestomach resembling small benign gastric polyps", GastrointestEndosc (2008)
- 황상연, "유방절제술 17년 후 조기위암으로 오인된 유방암의 위전이 1예", 대한소화기학회지, 46(6), pp.481~484 (2005), 대한소화기학회
- Lopez R., "Metastaticcarcinoma of the breast resembling early gastric carcinoma", Mayo Clin Proc, 76, pp.205~7 (2001)
- Borst MJ, "Metastatic patterns of invasive lobularversus invasive ductal carcinoma of the breast", Surgery, 114, pp.637~41 (1993)
- Bunting JS, "The pattern of spreadand survival in 596 cases of breast cancer related to clinicalstaging and histological grade", Clin Radiol, 27, pp.9~15 (1976)
- 최경석, "유방암의 위전이 1예", 대한내과학회지, 71(5), pp.567~572 (2006), 대한내과학회
- 손병호, "유방암 환자에서 타장기에 발생한 원발성 악성종양의 임상적 특성", 한국유방암학회지, 10(4), pp.263~268 (2007), 한국유방암학회
- Jeon SH, "A case of gastric metastasis from breast carcinoma manifestedby upper gastrointestinal bleeding", Korean J GastrointestEndosc, 24, pp.220~24 (2002)
- Viadana E, "An autopsy study of someroutes of dissemination of cancer of the breast", Br J Cancer, 27, pp.336~40 (1973)
- Chen JJ, "Endoscopic features of metastatictumors in the upper gastrointestinal tract", Endoscopy, 28, pp.249~53 (1996)
- Choi SH, "Metastatic involvementof the stomach by breast cancer", Cancer, 17, pp.791~7 (1964)
- Mohammed RA, "Lymphatic and angiogenic characteristics in breast cancer:morphometric analysis and prognostic implications", BreastCancer Res Treat (2008)