如意金黃散의 항산화 효과에 관한 실험적 연구
The Experimental Study of Yeouigeumhwang-san on Antioxidant Effects
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Abstract
Objectives : This experiment study was performed to investigate the antioxidant effects of Yeouigeumhwang-san(YUGHS). Methods : Antioxidant effects of YUGHS on HaCaT cell, that were measured by the scavenging for DPPH radical, the formation of intracellular GSH and the inhibition for ROS. Results : 1. YUGHS showed an oxidation inhibitory effect by decreasing the DPPH radicals. 2. Concentrations of 20 ㎍/㎖, 50 ㎍/㎖ YUGHS slightly increased the formation of intracellular GSH in HaCaT cell. 3. Concentration of 50 ㎍/㎖ YUGHS slightly inhibited the production of ROS in the HaCaT cell stimulated with H2O2, but it is not significant. Conclusions : These results indicate that YUGHS has antioxidant effects. If further study is performed, the use of YUGHS will be valuable and benificial in the therapy of inflammation..
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