Nd:YAG 레이저(λ = 1444 nm)를 이용한 연골 재성형 효과 규명
Evaluation of Effective Cartilage Reshaping using Nd:YAG laser (λ = 1444 nm)
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Mechanically deformed cartilage undergoes a temperature dependent phase transformation resulting in reshaping of cartilage. Laser-assisted cartilage reshaping (LCR) is recently introduced to recreate the underlying cartilage framework in structures such as ear, larynx, trachea, and nose. However, this procedure has not been fully supported by confirmed efficacy because of the lack of scientific research and its safety issues. The purpose of this study is to evaluate current laser sources to determine optimal laser wavelength for LCR using mathematical simulations and investigate optical, thermo-mechanical, and backscattering properties of cartilage after laser irradiation. The results showed that 1444 nm wavelength was effective for reshaping of cartilage with minimal thermal damage in the surrounded tissues by monte carlo simulations. Analysis of bend angle changes, thermo-mechanical characteristics, and backscattered properties may be useful to better identify the biophysical transformation responsible for stress relaxation in cartilage and develop an optical feedback control methodologies.
Abstract
Mechanically deformed cartilage undergoes a temperature dependent phase transformation resulting in reshaping of cartilage. Laser-assisted cartilage reshaping (LCR) is recently introduced to recreate the underlying cartilage framework in structures such as ear, larynx, trachea, and nose. However, this procedure has not been fully supported by confirmed efficacy because of the lack of scientific research and its safety issues. The purpose of this study is to evaluate current laser sources to determine optimal laser wavelength for LCR using mathematical simulations and investigate optical, thermo-mechanical, and backscattering properties of cartilage after laser irradiation. The results showed that 1444 nm wavelength was effective for reshaping of cartilage with minimal thermal damage in the surrounded tissues by monte carlo simulations. Analysis of bend angle changes, thermo-mechanical characteristics, and backscattered properties may be useful to better identify the biophysical transformation responsible for stress relaxation in cartilage and develop an optical feedback control methodologies.
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