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레이저에 의한 연골의 광학적 열적 특성변화 연구

Optical and Thermal Characteristic Studies of Cartilage by Laser Irradiation

윤종인|이연의
대한의용생체공학회 (The Korea Society Of Medical & Biological Engineering)|2011.09|의공학회지 (Journal of biomedical Engineering Research)|제32권 제3호|pp. 270-277

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참고문헌

키워드

Monte Carlo simulationlasercartilage reshapingoptical and thermal changeswater fluxbiophysical transformation

초록

Laser cartilage reshaping(LCR) is a promising method for reshaping cartilage by using laser irradiation to maintain permanently modifies its shape. However, this method has not been fully understood due to the limited scientific researches. The purpose of this study is to analyze optical and thermal characteristics of cartilage during laser irradiation. After analyzing Monte Carlo simulation for the comparison of laser fluence distributions with different laser wavelengths, the characterization of the spectral changes during Nd:YAG laser(λ = 1444 nm) irradiation was investigated in the ranges of 900-1700 nm with double integrating spheres. The surface temperature distribution changes during laser irradiation were investigated with an infrared camera. The quantitative measurements of optical and thermal characteristics in cartilage after laser irradiation were correlated with the transition of water flux(from bound to free water) and this study may be useful for better understanding of biophysical transformation phenomena in cartilage after laser heating.

Abstract

Laser cartilage reshaping(LCR) is a promising method for reshaping cartilage by using laser irradiation to maintain permanently modifies its shape. However, this method has not been fully understood due to the limited scientific researches. The purpose of this study is to analyze optical and thermal characteristics of cartilage during laser irradiation. After analyzing Monte Carlo simulation for the comparison of laser fluence distributions with different laser wavelengths, the characterization of the spectral changes during Nd:YAG laser(λ = 1444 nm) irradiation was investigated in the ranges of 900-1700 nm with double integrating spheres. The surface temperature distribution changes during laser irradiation were investigated with an infrared camera. The quantitative measurements of optical and thermal characteristics in cartilage after laser irradiation were correlated with the transition of water flux(from bound to free water) and this study may be useful for better understanding of biophysical transformation phenomena in cartilage after laser heating.

참고문헌 (32)

  1. F.F. Jaffe, "Water binding in the articular cartilage of rabbits", J. Bone Joint Surg. Am, 56, pp.1031~1039 (1974)
  2. E. Sobol, "Laser reshaping of cartilage", Biotechnol. Genet. Eng. Rev, 17, pp.553~631 (2000)
  3. S.C. Jiang, "Effects of dynamic change of tissue properties during laser-induced interstitial thermotherapy", Lasers Med. Sci, 19(4), pp.197~202 (2005)
  4. R. Wright, "Shape retention in porcine and, rabbit nasal septal cartilage using saline bath immersion and Nd:YAG laser irradiation", Lasers Surg. Med, 37, pp.201~209 (2005)
  5. C. Li, "Analysis of Nd:YAG laser-mediated thermal damage in rabbit nasal septal cartilage", Lasers Surg. Med, 39, pp.451~457 (2007)
  6. E. Helidonis, "Laser shaping of composite cartilage grafts", Am. J. Otolaryngol, 14(6), pp.410~412 (1993)
  7. E.N. Sobol, "Phase transformations and ablation in lasertreated solids", pp.316~321 (1995), John Wiley
  8. E. Sobol, "Mechanism of laser-induced stress relaxation in cartilage", Proc SPIE, pp.310~315 (1997)
  9. B. Wong, "Thermooptical response of cartilage during feedback-controlled laser-assisted reshaping", Proc SPIE, pp.380~391 (1997)
  10. M.R. Homicz, "A compositional analysis of human nasal septal cartilage", Arch. Facial Plast Surg, 5(1), pp.53~58 (2003)
  11. L.P. Cartner, "Cartilage and bone, Color textbook of histology. 3rded", pp.131~187 (2007), Saunders elsevir
  12. 윤진희, "Nd:YAG 레이저(λ = 1444 nm)를 이용한 연골 재성형 효과 규명", 의공학회지, 31(6), pp.472~480 (2010), 대한의용생체공학회
  13. Y. Chae, "Thermoforming of tracheal cartilage: viability, shape change, and mechanical behavior", Lasers Surg. Med, 40(8), pp.550~561 (2008)
  14. N. Jones, "A prospective randomised study of laser reshaping of cartilage in vivo", Lasers Med. Sci, 16(4), pp.284~290 (2001)
  15. D.W. Ebert, "Articular cartilage optical properties in the spectral range 300-850 nm", J. Biomed. Optics, 3(3), pp.326~333 (1998)
  16. 최익수, "레이저 연골 성형술", 대한이비인후과학회지 두경부외과학, 52(4), pp.296~301 (2009), 대한이비인후과학회
  17. G.A. Velegrakis, "In vitro ear cartilage shaping with carbon dioxide laser: An experimental study", Ann. Otol. Rhinol. Laryngol, 109, pp.119~128 (2000)
  18. M.L. Kaiser, "Cartilage regeneration in the rabbit nasal septum", Laryngoscope, 116(10), pp.1730~1734 (2006)
  19. S. Mordon, "Laser cartilage reshaping in an in vivo rabbit model using a 1.54 micron Er:Glass laser", Lasers Surg. Med, 34(4), pp.315~322 (2004)
  20. H.C. Lee, "Simultaneous dual-wavelength oscillation at 1357 nm and 1444 nm in a Kr-flashlamp pumped Nd:YAG laser", Optics Communications, 281(17), pp.4455~4458 (2008)
  21. Jong-In Youn, "A Comparison of Wavelength Dependence for Laser-assisted Lipolysis Effect Using Monte Carlo Simulation", Journal of the Optical Society of Korea, 13(2), pp.267~271 (2009), 한국광학회
  22. L. Wang, "MCML-Monte Carlo modeling of light transport in multi-layered tissues", Comput. Methods Programs Biomed, 47(2), pp.131~146 (1995)
  23. 임수현, "Monte Carlo 시뮬레이션을 이용한 생체 조직내의 광선량 측정", J. Biomed. Eng. Res, 20(2), pp.199~204 (1999)
  24. M. Hammer, "Optical properties of ocular fundus tissues-an in vitro study using the double-integrating-sphere technique and inverse Monte Carlo simulation", Phys. Med. Biol, 40(6), pp.963~978 (1995)
  25. S.Prahl, "Inverse Adding-Doubling for optical property measurement" (2007), Oregon Medical Laser Center
  26. G. Spahn, "Evaluation of cartilage defects with near-infrared spectroscopy( NIR): An ex vivo study", Med. Eng. Phys, 30(3), pp.285~292 (2008)
  27. P. Taroni, "Absorption of collagen: effects on the estimate of breast composition and related diagnostic implications", J. Biomed. Opt, 12(1) (2007)
  28. Y. Chae, "Effect of water content on enthalpic relaxations in porcine septal cartilage", J. Therm. Anal. and Calorim, 95, pp.937~943 (2009)
  29. A. Sviridov, "The effect of Holmium laser radiation on stress, temperature and structure of cartilage", Lasers Med. Sci, 13(1), pp.73~77 (1998)
  30. V.N. Bagratashvili, "Thermal and diffusion processes in laser-induced stress relaxation and reshaping of cartilage", J. Biomechanics, 30(8), pp.813~817 (1997)
  31. N. Ignatieva, "Molecular processes and structural alterations in laser reshaping of cartilage", Laser Phys. Lett, 4(10), pp.749~753 (2007)
  32. I.S. Choi, "Viability of human septal cartilage after 1.45 microm diode laser irradiation", Lasers Surg. Med, 4(8), pp.562~569 (2008)

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