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Anti-N-Methyl-D-Aspartate Receptor Encephalitis Presenting Progressive Dyslexia: A Case Report

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Background Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis was discovered less than 10 years ago. Its symptoms andcharacteristics are not well-defined yet. We experienced a case of anti-NMDA receptor encephalitis with phonemic paraphasia and acalculiathat were not classical characteristics. Case Report A 44-year-old woman started to show dyslexia, phonemic paraphasia, and dyscalculia. These symptoms were gradually worseningfor over 30 days. Various brain images were not helpful for primary diagnosis. Anti-NMDA receptor encephalitis was confirmed in twodifferent laboratories. The patient started to recover with various immunosuppressive therapies. Conclusions Anti-NMDA receptor encephalitis can have various symptoms, including phonemic paraphasia and acalculia.

Abstract

Background Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis was discovered less than 10 years ago. Its symptoms andcharacteristics are not well-defined yet. We experienced a case of anti-NMDA receptor encephalitis with phonemic paraphasia and acalculiathat were not classical characteristics. Case Report A 44-year-old woman started to show dyslexia, phonemic paraphasia, and dyscalculia. These symptoms were gradually worseningfor over 30 days. Various brain images were not helpful for primary diagnosis. Anti-NMDA receptor encephalitis was confirmed in twodifferent laboratories. The patient started to recover with various immunosuppressive therapies. Conclusions Anti-NMDA receptor encephalitis can have various symptoms, including phonemic paraphasia and acalculia.

참고문헌 (13)

  1. Dalmau J, "Limbic encephalitis: the new cell membrane antigens and a proposal of clinical-immunological classification with therapeutic implications", Neurologia, 22, pp.526~537 (2007)
  2. Barry H, "Anti-N-methyl-d-aspartate receptor encephalitis: review of clinical presentation, diagnosis and treatment", BJPsych Bull, 39, pp.19~23 (2015)
  3. Wang W, "Anti-NMDA receptor encephalitis: clinical characteristics, predictors of outcome and the knowledge gap in southwest China", Eur J Neurol (2015)[DOI]
  4. antibodies in patients with schizophrenia and related psychoses: a systematic review and meta-analysis, "Psychol Med", 2014, 2475~2487
  5. Deiva K, "Sudden and isolated Broca’s aphasia: a new clinical phenotype of anti NMDA receptor antibodies encephalitis in children", Eur J Paediatr Neurol, 18, pp.790~792 (2014)
  6. Reid DK, "Neurological picture. Anti-NMDA-receptor encephalitis: unusual presentation of an uncommon condition", J Neurol Neurosurg Psychiatry, 84, pp.69~70 (2013)
  7. Hacohen Y, "NMDA receptor antibodies associated with distinct white matter syndromes", Neurol Neuroimmunol Neuroinflamm, 1, pp.e2~ (2014)
  8. Finke C, "Structural Hippocampal Damage Following Anti-N-Methyl-DAspartate Receptor Encephalitis", Biol Psychiatry (2015)
  9. Schmitt SE, "Extreme delta brush: a unique EEG pattern in adults with anti-NMDA receptor encephalitis", Neurology, 79, pp.1094~1100 (2012)
  10. VanHaerents S, "Early and persistent ‘extreme delta brush’ in a patient with anti-NMDA receptor encephalitis", Epilepsy Behav Case Rep, 2, pp.67~70 (2014)
  11. Iizuka T, "Clinical features and pathogenesis of anti-NMDA receptor encephalitis", Rinsho Shinkeigaku, 48, pp.920~922 (2008)
  12. Wang R, "CSF findings in patients with anti-N-methyl-D-aspartate receptor-encephalitis", Seizure, 29, pp.137~142 (2015)
  13. De Nayer AR, "A subacute behavioral disorder in a female adolescent. Autoimmune anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma", Biol Psychiatry, 66, pp.e13~e14 (2009)

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