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청각 연구에서 기능적 뇌 영상 기술 적용에 대한 고찰: 난청을 중심으로

A review of the Implementation of Functional Brain Imaging Techniques in Auditory Research focusing on Hearing Loss

신재영|설혜윤
대한의용생체공학회 (The Korea Society Of Medical & Biological Engineering)|2024.02|의공학회지 (Journal of biomedical Engineering Research)|제45권 제1호|pp. 26-36|DOI 10.9718/JBER.2024.45.1.26

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키워드

EEGReviewfMRIHearing lossFunctional brain imaging

초록

Functional brain imaging techniques have been used to diagnose psychiatric disorders such as dementia, de- pression, and autism. Recently, these techniques have also been actively used to study hearing loss. The present study re- viewed the application of the functional brain imaging techniques in auditory research, especially those focusing on hear- ing loss, over the past decade. EEG, fMRI, fNIRS, MEG, and PET have been utilized in auditory research, and the num- ber of research studies using these techniques has been increasing. In particular, fMRI and EEG were the most frequently used technique in auditory research. EEG studies mostly used event-related designs to analyze the direct relationship between stimulus and the related response, and in fMRI studies, resting-state functional connectivity and block designs were utilized to analyze alterations in brain functionality in hearing-related areas. In terms of age, while studies involving children mainly focused on congenital and pre- and post-lingual hearing loss to analyze developmental characteristics with and without hearing loss, those involving adults focused on age-related hearing loss to investigate changes in the charac- teristics of the brain based on the presence of hearing loss and the use of a hearing device. Overall, ranging from EEG to PET, various functional brain imaging techniques have been used in auditory research, but it is difficult to perform a com- prehensive analysis due to the lack of consistency in experimental designs, analysis methods, and participant characteris- tics. Thus, it is necessary to develop standardized research protocols to obtain high-quality clinical and research evidence.

Abstract

Functional brain imaging techniques have been used to diagnose psychiatric disorders such as dementia, de- pression, and autism. Recently, these techniques have also been actively used to study hearing loss. The present study re- viewed the application of the functional brain imaging techniques in auditory research, especially those focusing on hear- ing loss, over the past decade. EEG, fMRI, fNIRS, MEG, and PET have been utilized in auditory research, and the num- ber of research studies using these techniques has been increasing. In particular, fMRI and EEG were the most frequently used technique in auditory research. EEG studies mostly used event-related designs to analyze the direct relationship between stimulus and the related response, and in fMRI studies, resting-state functional connectivity and block designs were utilized to analyze alterations in brain functionality in hearing-related areas. In terms of age, while studies involving children mainly focused on congenital and pre- and post-lingual hearing loss to analyze developmental characteristics with and without hearing loss, those involving adults focused on age-related hearing loss to investigate changes in the charac- teristics of the brain based on the presence of hearing loss and the use of a hearing device. Overall, ranging from EEG to PET, various functional brain imaging techniques have been used in auditory research, but it is difficult to perform a com- prehensive analysis due to the lack of consistency in experimental designs, analysis methods, and participant characteris- tics. Thus, it is necessary to develop standardized research protocols to obtain high-quality clinical and research evidence.

참고문헌 (120)

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