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청각 기능성 자기공명영상(Auditory Functional Magnetic Resonance Imaging) 연구, 어떻게 시작할 것인가

Auditory Functional Magnetic Resonance Imaging:How to Begin

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참고문헌

주제분류이비인후과학

초록

뇌간의 와우핵(CN)으로부터 청각피질(AC)에 이르는 인 체 청각 중추의 반응을 연구하기 위한 기능성 자기공명영 상기법이 확립되어 이제는 다양한 방면의 연구가 가능하다. 특히 뇌간 청각중추의 성공적인 fMRI연구를 위해서는 효 율적인 study design의 선택, 자극 음의 측정 및 전달 방 식의 확립, 자극 음의 선택 등이 중요하며, 영상의학 분야 및 영상 분석 전문가의 참여와 적극적인 협력이 필수적이 다. 이러한 fMRI연구 기법을 통해, 말초 청각장애에 의해 유발되는 중추 청각 경로의 신경 가소성에 대한 연구를 심 화시킬 수 있으며, 대뇌의 resting state에 대한 연구에 data-driven analysis를 적용함으로써 이명의 기전과 연관 된 청각계의 역할을 조명할 수 있고, 나아가 청각계와 다 른 감각계, 또는 정서, 인지, 및 운동계와의 기능적 연관성 을 규명할 수 있을 것이다.

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