Constructing a Composite Score for the Seoul Neuropsychological Screening Battery-Core
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초록
Background and Purpose The brief version of the Seoul Neuropsychological Screening Battery (SNSB), the SNSB-Core (SNSB-C), hasbeen developed. Although each subtest score of the SNSB-C provides information on different features of broad cognitive functioning or impairment,a composite score is needed to identify the severity of global cognitive impairment. We aimed to develop and validate a compositescore of the SNSB-C that would provide a normative-based summary score of global cognitive functioning, especially for differentiating patientswith cognitive impairment from normal elderly. Methods A normative sample of 1067 elderly was used to develop a composite score of SNSB-C. The composite score was corrected for theeffects of age, years of education, and sex by the regression method. Patients with Alzheimer’s disease (n=41), vascular dementia (n=40), amnesticmild cognitive impairment (MCI) (n=73), vascular MCI (n=41), and Parkinson’s disease with MCI (n=41) were differentiated from anormal sample (n=70) by the uncorrected and corrected composite scores using receiver operating characteristic (ROC) curve analysis. Results Confirmatory factor analysis showed that the composite score equal weight to each standardized cognitive domain of SNSB-C isappropriate for indexing overall cognitive functioning. The corrected and uncorrected composite scores yielded a satisfactory size of the areaunder the ROC curve comparable to the Mini Mental State Examination (MMSE). Conclusions The composite scores of SNSB-C, especially the corrected score, provide an index of overall cognitive functioning, and theycan be used as an alternative to MMSE for screening patients with cognitive impairment.
Abstract
Background and Purpose The brief version of the Seoul Neuropsychological Screening Battery (SNSB), the SNSB-Core (SNSB-C), hasbeen developed. Although each subtest score of the SNSB-C provides information on different features of broad cognitive functioning or impairment,a composite score is needed to identify the severity of global cognitive impairment. We aimed to develop and validate a compositescore of the SNSB-C that would provide a normative-based summary score of global cognitive functioning, especially for differentiating patientswith cognitive impairment from normal elderly. Methods A normative sample of 1067 elderly was used to develop a composite score of SNSB-C. The composite score was corrected for theeffects of age, years of education, and sex by the regression method. Patients with Alzheimer’s disease (n=41), vascular dementia (n=40), amnesticmild cognitive impairment (MCI) (n=73), vascular MCI (n=41), and Parkinson’s disease with MCI (n=41) were differentiated from anormal sample (n=70) by the uncorrected and corrected composite scores using receiver operating characteristic (ROC) curve analysis. Results Confirmatory factor analysis showed that the composite score equal weight to each standardized cognitive domain of SNSB-C isappropriate for indexing overall cognitive functioning. The corrected and uncorrected composite scores yielded a satisfactory size of the areaunder the ROC curve comparable to the Mini Mental State Examination (MMSE). Conclusions The composite scores of SNSB-C, especially the corrected score, provide an index of overall cognitive functioning, and theycan be used as an alternative to MMSE for screening patients with cognitive impairment.
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