Accuracy of Korean-Mini-Mental Status Examination Based on Seoul Neuro-Psychological Screening Battery II Results
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참고문헌
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초록
Background: The Korean-Mini-Mental Status Examination (K-MMSE) is a dementia-screening test that can beeasily applied in both community and clinical settings. However, in 20% to 30% of cases, the K-MMSE produces afalse negative response. This suggests that it is necessary to evaluate the accuracy of K-MMSE as a screening test fordementia, which can be achieved through comparison of K-MMSE and Seoul Neuropsychological Screening Battery(SNSB)-II results. Methods: The study included 713 subjects (male 534, female 179; mean age, 69.3±6.9 years). All subjects were assessedusing K-MMSE and SNSB-II tests, the results of which were divided into normal and abnormal in 15 percentilestandards. Results: The sensitivity of the K-MMSE was 48.7%, with a specificity of 89.9%. The incidence of false positive andnegative results totaled 10.1% and 51.2%, respectively. In addition, the positive predictive value of the K-MMSE was87.1%, while the negative predictive value was 55.6%. The false-negative group showed cognitive impairments inregions of memory and executive function. Subsequently, in the false-positive group, subjects demonstrated reducedperformance in memory recall, time orientation, attention, and calculation of K-MMSE items. Conclusion: The results obtained in the study suggest that cognitive function might still be impaired even if an individualobtained a normal score on the K-MMSE. If the K-MMSE is combined with tests of memory or executivefunction, the accuracy of dementia diagnosis could be greatly improved.
Abstract
Background: The Korean-Mini-Mental Status Examination (K-MMSE) is a dementia-screening test that can beeasily applied in both community and clinical settings. However, in 20% to 30% of cases, the K-MMSE produces afalse negative response. This suggests that it is necessary to evaluate the accuracy of K-MMSE as a screening test fordementia, which can be achieved through comparison of K-MMSE and Seoul Neuropsychological Screening Battery(SNSB)-II results. Methods: The study included 713 subjects (male 534, female 179; mean age, 69.3±6.9 years). All subjects were assessedusing K-MMSE and SNSB-II tests, the results of which were divided into normal and abnormal in 15 percentilestandards. Results: The sensitivity of the K-MMSE was 48.7%, with a specificity of 89.9%. The incidence of false positive andnegative results totaled 10.1% and 51.2%, respectively. In addition, the positive predictive value of the K-MMSE was87.1%, while the negative predictive value was 55.6%. The false-negative group showed cognitive impairments inregions of memory and executive function. Subsequently, in the false-positive group, subjects demonstrated reducedperformance in memory recall, time orientation, attention, and calculation of K-MMSE items. Conclusion: The results obtained in the study suggest that cognitive function might still be impaired even if an individualobtained a normal score on the K-MMSE. If the K-MMSE is combined with tests of memory or executivefunction, the accuracy of dementia diagnosis could be greatly improved.
참고문헌 (16)
- Han S, "Screening instruments for dementia: screening tests of dementia", The Korean Association for Dementia, ~ (2010)
- Chin JH, "Dementia: a clinical approach", pp.75~95 (2006), Academia Publishing Co
- Folstein MF, "“Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician", J Psychiatr Res, 12, pp.189~198 (1975)
- Lancu I, "The minimental state examination: an up-to-date review", Harefuah, 145, pp.687~690 (2006)
- Bondi MW, "Neuropsychological assessment of neuropsychiatric disorders", pp.164~199 (1996), Oxford University Press
- Kang Y, "A validity study on the Korean Mini-Mental State Examination (K-MMSE) in dementia patients", J Korean Neurol Assoc, 15, pp.300~308 (1997)
- Park JH, "Standardization of Korean of the Korean Mini-Mental State Examination (K-MMSE) for use in the elderly: part II, diagnostic validity", J Korean Neuropsychiatr Assoc, 28, pp.508~513 (1989)
- Nelson A, "Bedside cognitive screening instruments:a critical assessment", J Nerv Ment Dis, 174, pp.73~83 (1986)
- 강연욱, "K-MMSE(Korean-Mini Mental State Examination)의 노인 규준 연구", 한국심리학회지:일반, 25(2), pp.1~12 (2006), 한국심리학회
- Fillenbaum GG, "Relation of health and demographic characteristics to Mini-Mental State Examination score among community residents", Psychol Med, 18, pp.719~726 (1988)
- O’Connor DW, "The influence of education, social class and sex on Mini-Mental State scores", Psychol Med, 19, pp.771~776 (1989)
- 오은아, "치매선별검사로서 K-MMSE의 타당도 연구: 종합적인 신경심리학적 평가와의 비교", Dementia and Neurocognitive Disorders(대한치매학회지), 9(1), pp.8~12 (2010), 대한치매학회
- Kang Y, "Seoul Neuropsychological Screening Battery (SNSB-II)" (2012), Human Brain Research & Consulting Co
- American Psychiatric Association, "Diagnostic and statistical manual of mental disorders: DSM-IV" (1994), American Psychiatric Association
- Axelrod BN, "Sensitivity of the Mini-Mental State Examination to frontal lobe dysfunction in normal aging", J Clin Psychol, 48, pp.68~71 (1992)
- Hoops S, "Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease", Neurology, 73, pp.1738~1745 (2009)