당뇨환자의 창상에서 분리된 반코마이신 내성 Enterococcus avium
Vancomycin-resistant Enterococcus avium Isolated from the Wound of a Patient with Diabetes Mellitus
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Enterococcus avium (E. avium)은 조류에서 가장 많이 발견되며, 사람에서 병원균으로 보고된 예는 드물다. E. avium에 의한 감염에 대한 연구가 일부 보고가 되었지만, 임상 양상 및 항생제 감수성에 대해서는 알려진 바가 적다. 저자들은 당뇨환자의 창상조직에서 vanA를 생성하는 vancomycin 내성 E. avium을 동정하여보고하는 바이다. vancomycin 내성 E. avium이 장내 군집 VRE에서 드물게 관찰되기는 했지만, 임상검체에서 분리된 증례보고는매우 드문 것으로 판단된다. 균주는 표현성상 및 16S rRNA 염기서열분석을 통해 확인되었다.
Abstract
Enterococcus avium, very commonly found in birds, is rarely reported as a human pathogen. Although several studies have focused on cases of infection with E. avium, little is known about the clinical features of E. avium infection and the antimicrobial susceptibility pattern of E. avium. We isolated vanA-producing vancomycin-resistant E. avium from specimen obtained from the wound of a patient with diabetes mellitus. Vancomycin-resistant E. avium is rarely observed among the vancomycin-resistant enterococci colonizing the intestine, and there are very few reports of vancomycin-resistant E. avium isolated from clinical specimens. Here we confirmed that the clinical isolate was E. avium on the basis of phenotypic characterization and the results of 16S rRNA sequence analysis.
참고문헌 (21)
- Huycke MM, "Multiple-drug resistant enterococci: the nature of the problem and an agenda for the future", Emerg Infect Dis, 4, pp.239~249 (1998)
- Fisher K, "The ecology, epidemiology and virulence of Enterococcus", Microbiology, 155, pp.1749~1757 (2009)
- Na S, "Enterococcus avium bacteremia: a 12-year clinical experience with 53 patients", Eur J Clin Microbiol Infect Dis, 31, pp.303~310 (2012)
- 이경원, "Further Increases in Carbapenem-, Amikacin-, and Fluoroquinolone-Resistant Isolates of Acinetobacter spp. and P. aeruginosa in Korea: KONSAR Study 2009", Yonsei Medical Journal, 52(5), pp.793~802 (2011), 연세대학교의과대학
- Papaparaskevas J, "Epidemiology of multiresistant Enterococcus avium isolates in a Greek tertiary care hospital", Int J Antimicrob Agents, 20, pp.432~437 (2002)
- Patel R, "Steckelberg JM. Bacteremia due to Enterococcus avium", Clin Infect Dis, 17, pp.1006~1011 (1993)
- Lee SY, "Fecal colonization with vancomycin-resistant enterococci (VRE): Clinical and epidemiologic features", Korean J Lab Med, 17, pp.743~756 (1997)
- Jeong SH, "Intestinal colonization of vancomycin-resistant enterococci", Korean J Nosocomial Infect Control, 3, pp.41~47 (1998)
- Lee PP, "Vancomycin-Resistant Enterococcus avium Infections: Report of 2 Cases and a Review of Enterococcus avium Infections", Infect Dis Clin Pract, 12, pp.239~244 (2004)
- Clinical and Laboratory Standards Institute, "Performances standards for antimicrobial susceptibility testing", 22th information supplement M100-S22. Wayne, PA, USA CLSI, ~ (2012)
- Schuurman T, "Prospective study of use of PCR amplification and sequencing of 16S ribosomal DNA from cerebrospinal fluid for diagnosis of bacterial meningitis in a clinical setting", J Clin Microbiol, 42, pp.734~740 (2004)
- Jones S, "Microbiologically confirmed meningoencephalitis due to Enterococcus avium: a first report", J Infect, 54, pp.e129~e131 (2007)
- Mirzoyev Z, "Enterococcus avium endocarditis", Scand J Infect Dis, 36, pp.876~878 (2004)
- Mohanty S, "Brain abscess due to Enterococcus avium", Am J Med Sci, 329, pp.161~162 (2005)
- Swaminathan S, "Enterococcus avium endocarditis in an infant with tetralogy of Fallot", Pediatr Cardiol, 20, pp.227~228 (1999)
- Dworniczek E, "Enterococcus in wound infections: Virulence and antimicrobial resistance", Acta Microbiol Immunol Hung, 59, pp.263~269 (2012)
- 이위교, "Characterization of a Vancomycin-resistant Enterococcus faecium Outbreak Caused by 2 Genetically Different Clones at a Neonatal Intensive Care Unit", Annals of Laboratory Medicine, 32(1), pp.82~86 (2012), 대한진단검사의학회
- Montecalvo MA, "Natural history of colonization with vancomycin-resistant Enterococcus faecium", Infect Control Hosp Epidemiol, 16, pp.680~685 (1995)
- DiazGranados CA, "Comparison of mortality associated with vancomycin-resistant and vancomycin-susceptible enterococcal bloodstream infections: a meta-analysis", Clin Infect Dis, 41, pp.327~333 (2005)
- Sifaoui F, "Vancomycin dependence in a vanA-producing Enterococcus avium strain with a nonsense mutation in the natural D-Ala-D-Ala ligase gene", Antimicrob Agents Chemother, 41, pp.1409~ (1997)
- Rosato A, "Inducible and constitutive expression of resistance to glycopeptides and vancomycin dependence in glycopeptide-resistant Enterococcus avium", Antimicrob Agents Chemother, 39, pp.830~833 (1995)
