Vancomycin Resistance due to vanA Gene Expression in an Aerococcus viridans Isolate: First Case in Korea
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Dear Editor, Aerococcus viridans is a catalase-negative gram-positive coccus that appears in clusters, tetrads, or irregular arrangements [1]. This organism is generally considered as a contaminant in clinical cultures, but is also infrequently reported as a clinically significant isolate that causes endocarditis, bacteremia, spondylodiscitis, and urinary tract infections [2-5]. Although most A. viridans strains were susceptible to penicillin and other commonly used antibiotics, Uh et al [6] described a case of bacteremia caused by an A. viridans strain showing high resistance to penicillin, erythromycin, clindamycin, and ceftriaxone. In 2014, Zhou et al [7] reported a peritoneal dialysis-related infection caused by vancomycin-resistant A. viridans harboring the vanA gene. We report a case of a vancomycin-resistant A. viridans isolate obtained from an excisional biopsy wound. As far as we know, no study regarding vancomycin-resistant A. viridans has yet been published in Korea.
Abstract
Dear Editor, Aerococcus viridans is a catalase-negative gram-positive coccus that appears in clusters, tetrads, or irregular arrangements [1]. This organism is generally considered as a contaminant in clinical cultures, but is also infrequently reported as a clinically significant isolate that causes endocarditis, bacteremia, spondylodiscitis, and urinary tract infections [2-5]. Although most A. viridans strains were susceptible to penicillin and other commonly used antibiotics, Uh et al [6] described a case of bacteremia caused by an A. viridans strain showing high resistance to penicillin, erythromycin, clindamycin, and ceftriaxone. In 2014, Zhou et al [7] reported a peritoneal dialysis-related infection caused by vancomycin-resistant A. viridans harboring the vanA gene. We report a case of a vancomycin-resistant A. viridans isolate obtained from an excisional biopsy wound. As far as we know, no study regarding vancomycin-resistant A. viridans has yet been published in Korea.
참고문헌 (10)
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