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Actinotignum schaalii 에 의한 요로감염증 1예

A Case of Urinary Tract Infection Caused by the Emerging Uropathogen Actinotignum schaalii

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참고문헌

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초록

Actinotignum schaalii는 신종 요로감염균의 일종이지만, 일반적인 배양법과 표현형 분석법으로는 이를 검출하고 동정하기 어려운 특징이 있다. 저자들은 79세 전립선암 환자에서 발생한 A. schaalii 요로감염증 국내 첫 증례를 보고하고자 한다. 환자의 소변검체에서 배양 이틀 후 그람양성 막대균이 배양되었고, 이는 MALDITOF 질량분석기와 16S rDNA 염기서열분석으로 A. schaalii로 동정되었다.

Abstract

Actinotignum schaalii is an emerging uropathogen; however, routine culture protocols and usual phenotypic methods do not allow for easy detection and identification. Herein, we report the first Korean case of urinary tract infection caused by A. schaalii in a 79-year-old patient with prostate cancer. A gram-positive rod bacterium was isolated from the patient's urine after 2 days of culture and identified as A. schaalii using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and DNA target sequencing.

참고문헌 (19)

  1. Lotte R, "Actinotignum schaalii(formerly Actinobaculum schaalii) : a newly recognized pathogen-review of the literature", Clin Microbiol Infect, 22, pp.28~36 (2016)
  2. Tena D, "Skin and soft-tissue infections caused by Actinobaculum schaalii : report of two cases and literature review", Anaerobe, 28, pp.95~97 (2014)
  3. Haller P, "Vertebral osteomyelitis caused by Actinobaculum schaalii : a difficult-to-diagnose and potentially invasive uropathogen", Eur J Clin Microbiol Infect Dis, 26, pp.667~670 (2007)
  4. Hoenigl M, "Endocarditis caused by Actinobaculum schaalii, Austria", Emerg Infect Dis, 16, pp.1171~1173 (2010)
  5. Clinical and Laboratory Standards Institute, "Interpretive criteria for identification of bacteria and fungi by DNA target sequencing; approved guideline. CLSI document MM18-A", Clinical and Laboratory Standards Institute, ~ (2008)
  6. Yassin AF, "Dissection of the genus Actinobaculum: Reclassification of Actinobaculum schaalii Lawson et al. 1997 and Actinobaculum urinale Hall et al. 2003 as Actinotignum schaalii gen. nov., comb. nov. and Actinotignum urinale comb. nov., description of Actinotignum sanguinis sp. nov. and emended descriptions of the genus Actinobaculum and Actinobaculum suis; and re-examination of the culture deposited as Actinobaculum massiliense CCUG 47753T (=DSM 19118T), revealing that it does not represent a strain of this species", Int J Syst Evol Microbiol, 65, pp.615~624 (2015)
  7. Lawson PA, "Characterization of some Actinomyces-like isolates from human clinical specimens: reclassification of Actinomyces suis (Soltys and Spratling) as Actinobaculum suis comb. nov. and description of Actinobaculum schaalii sp. nov", Int J Syst Bacteriol, 47, pp.899~903 (1997)
  8. Fendukly F, "Isolation of Actinobaculum schaalii and Actinobaculum urinale from a patient with chronic renal failure", J Clin Microbiol, 43, pp.3567~3569 (2005)
  9. Hall V, "Actinobaculum urinale sp. nov., from human urine", Int J Syst Evol Microbiol, 53, pp.679~682 (2003)
  10. Cattoir V, "Actinobaculum schaalii : review of an emerging uropathogen", J Infect, 64, pp.260~267 (2012)
  11. Stevens RP, "Actinotignum(formerly Actinobaculum)schaalii : a review of MALDI-TOF for identification of clinical isolates, and a proposed method for presumptive phenotypic identification", Pathology, 48, pp.367~371 (2016)
  12. Nielsen HL, "Actinobaculum schaalii: a common cause of urinary tract infection in the elderly population. Bacteriological and clinical characteristics", Scand J Infect Dis, 42, pp.43~47 (2010)
  13. Foxman B, "Epidemiology of urinary tract infections: incidence, morbidity, and economic costs", Am J Med, 113(S1A), pp.5S~13S (2002)
  14. McKew G, ""Probable contaminants"no more : rapid identification of Gram-positive rods leads to improved clinical care", J Clin Microbiol, 51, pp.1641~ (2013)
  15. Tuuminen T, "Actinobaculum schaalii : identification with MALDI-TOF", New Microbes New Infect, 2, pp.38~41 (2014)
  16. Cattoir V, "In vitro susceptibility of Actinobaculum schaalii to 12 antimicrobial agents and molecular analysis of fluoroquinolone resistance", J Antimicrob Chemother, 65, pp.2514~2517 (2010)
  17. Reinhard M, "Ten cases of Actinobaculum schaalii infection : clinical relevance, bacterial identification, and antibiotic susceptibility", J Clin Microbiol, 43, pp.5305~5308 (2005)
  18. Wolfe AJ, "Evidence of uncultivated bacteria in the adult female bladder", J Clin Microbiol, 50, pp.1376~1383 (2012)
  19. Olsen AB, "Actinobaculum schaalii, a commensal of the urogenital area", BJU Int, 112, pp.394~397 (2013)

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