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Three cases of concomitant acanthosis nigricans with confluent and reticulated papillomatosis in obese patients

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초록

Acanthosis nigricans (AN) is characterized by symmetric, velvety, gray-brown hypertrophied plaques most commonly on the axillae and neck. Confluent and reticulated papillomatosis (CRP) is manifested by papules in the mid-chest that coalesce in the midline, and are arranged in a reticulated pattern peripherally. Both diseases are known to be related to endocrinopathies such as diabetes mellitus (DM), an insulin resistant state and obesity with unknown mechanisms. Herein, we presented three cases of concomitant acanthosis nigricans with confluent and reticulated papillomatosis in obese patients.

Abstract

Acanthosis nigricans (AN) is characterized by symmetric, velvety, gray-brown hypertrophied plaques most commonly on the axillae and neck. Confluent and reticulated papillomatosis (CRP) is manifested by papules in the mid-chest that coalesce in the midline, and are arranged in a reticulated pattern peripherally. Both diseases are known to be related to endocrinopathies such as diabetes mellitus (DM), an insulin resistant state and obesity with unknown mechanisms. Herein, we presented three cases of concomitant acanthosis nigricans with confluent and reticulated papillomatosis in obese patients.

참고문헌 (7)

  1. Karen RH, "Acanthosis nigricans in dermatology in general medicine", pp.1796~1801 (2003), McGraw-Hill
  2. Hamilton D, "Confluent and reticulated papillomatosis of Gougerot and Carteaud", J Am Acad Dermatol, 2, pp.401~410 (1980)
  3. Mutasim DF, "Confluent and reticulated papillomatosis without papillomatosis", J Am Acad Dermatol, 49, pp.1182~1184 (2003)
  4. Díiez E, "Confluent and reticulated papillomatosis without papillomatosis", J Am Acad Dermatol, 52, pp.E8~ (2005)
  5. Hirokawa M, "Confluent and reticulated papillomatosis: a case with concurrent acanthosis nigricans associated with obesity and insulin resistance", Dermatology, 188, pp.148~151 (1994)
  6. Cannavòo SP, "Confluent and reticulated papillomatosis and acanthosis nigricans in an obese girl: two distinct pathologies with a common pathogenetic pathway or a unique entity dependent on insulin resistance", J Eur Acad Dermatol Venereol, 20, pp.478~480 (2006)
  7. Torley D, "Genes, growth factor and acanthosis nigricans", Br J Dermatol, 147, pp.1096~1101 (2002)

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