Solitary Congenital Erosion in a Newborn: Report of a Solitary Congenital Self-Healing Reticulohistiocytosis
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Congenital self-healing reticulohistiocytosis (CSHRH) is arare, cutaneous, self-limited form of Langerhans cell histiocytosis. Whereas multiple lesions are common, a solitarylesion is rare. A 14-day-old neonate presented with a solitary,5-mm, oval, reddish, and eroded papule with crust on the leftthigh that had existed since birth. No systemic involvementwas found. Histopathology revealed dense infiltration oflarge histiocytes with scattered eosinophils and lymphocytesin the dermis. Immunohistochemistry showed S-100 andCD1a positivity. Two months later, the skin lesion involutedspontaneously, without evidence of recurrence and extracutaneousinvolvement. On the basis of the characteristicclinical course and typical histopathological findings, adiagnosis of solitary CSHRH was made.
Abstract
Congenital self-healing reticulohistiocytosis (CSHRH) is arare, cutaneous, self-limited form of Langerhans cell histiocytosis. Whereas multiple lesions are common, a solitarylesion is rare. A 14-day-old neonate presented with a solitary,5-mm, oval, reddish, and eroded papule with crust on the leftthigh that had existed since birth. No systemic involvementwas found. Histopathology revealed dense infiltration oflarge histiocytes with scattered eosinophils and lymphocytesin the dermis. Immunohistochemistry showed S-100 andCD1a positivity. Two months later, the skin lesion involutedspontaneously, without evidence of recurrence and extracutaneousinvolvement. On the basis of the characteristicclinical course and typical histopathological findings, adiagnosis of solitary CSHRH was made.
참고문헌 (13)
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