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A Case of Benign Cephalic Histiocytosis

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초록

Benign cephalic histiocytosis (BCH) is a rare non-Langerhans cell histiocytosis of unknown etiology. Clinically, lesions are characterized by small, red-to-yellow papules distributed mainly on the head, face, neck, and shoulders of infants and children. Histopathological specimens show massive histiocytic infiltration of the superficial dermis. Immunohistochemically,they are positive for CD68, but negative for CD1a and S-100. Two cases have been reported so far in the relevant work published in Korean literature. Herein, we report on an additional case of BCH. (Ann Dermatol 23(S1)S16∼S19, 2011)

Abstract

Benign cephalic histiocytosis (BCH) is a rare non-Langerhans cell histiocytosis of unknown etiology. Clinically, lesions are characterized by small, red-to-yellow papules distributed mainly on the head, face, neck, and shoulders of infants and children. Histopathological specimens show massive histiocytic infiltration of the superficial dermis. Immunohistochemically,they are positive for CD68, but negative for CD1a and S-100. Two cases have been reported so far in the relevant work published in Korean literature. Herein, we report on an additional case of BCH. (Ann Dermatol 23(S1)S16∼S19, 2011)

참고문헌 (13)

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  3. 정진섭, "양성 두부 조직구증 1예", 대한피부과학회지, 46(9), pp.1292~1295 (2008), 대한피부과학회
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  5. Jih DM, "Benign cephalic histiocytosis: a case report and review", J Am Acad Dermatol, 47, pp.908~913 (2002)
  6. Zelger BG, "Solitary giant xanthogranuloma and benign cephalic histiocytosis--variants of juvenile xanthogranuloma", Br J Dermatol, 133, pp.598~604 (1995)
  7. Rodriguez-Jurado R, "Benign cephalic histiocytosis progressing into juvenile xanthogranuloma: a non-Langerhans cell histiocytosis transforming under the influence of a virus", Am J Dermatopathol, 22, pp.70~74 (2000)
  8. Sidwell RU, "Is disseminated juvenile xanthogranulomatosis benign cephalic histiocytosis", Pediatr Dermatol, 22, pp.40~43 (2005)
  9. Weston WL, "Benign cephalic histiocytosis with diabetes insipidus", Pediatr Dermatol, 17, pp.296~298 (2000)
  10. Saez-De-Ocariz M, "Benign cephalic histiocytosis preceding the development of insulin-dependent diabetes mellitus", Pediatr Dermatol, 23, pp.101~102 (2006)
  11. Watabe H, "Case 2: benign cephalic histiocytosis", Clin Exp Dermatol, 27, pp.341~342 (2002)
  12. Dadzie O, "Benign cephalic histiocytosis in a British-African child", Pediatr Dermatol, 22, pp.444~446 (2005)
  13. Hasegawa S, "Japanese case of benign cephalic histiocytosis", J Dermatol, 36, pp.69~71 (2009)

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