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파킨슨병 고열 증후군에 병발한 도파민 조절장애 증후군 1예

A Case of Dopamine Dysregulation Syndrome with Concurrent Parkinsonism Hyperpyrexia Syndrome

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초록

Abstract

A few patients with Parkinson’s disease (PD) crave large amounts of levodopa therapy far beyond those needed to alleviate their symptoms, even in the state of overdose complication. Such harmful pattern of compulsive dopaminergic drug use is called as dopamine dysregulation syndrome (DDS). We report a chronic stage PD patient presenting with high fever and altered mentality, who had the DDS as well as the Parkinsonism hyperpyrexia syndrome (PHS).

참고문헌 (10)

  1. "Compulsive use of dopamine replacement therapy in Parkinson's disease: reward systems gone awry?", 2, pp.595~604 (2003)
  2. "Dopamine dysregulation syndrome in Parkinson's disease", 17, pp.393~398 (2004)
  3. "Compulsive drug use linked to sensitized ventral striatal dopamine transmission", 59, pp.852~858 (2006)
  4. "Factors influencing susceptibility to compulsive dopaminergic drug use in Parkinson disease", 65, pp.1570~1574 (2005)
  5. "Malignantsyndrome in Parkinson's disease: concept and review of the literature", 9, pp.3~9 (2003)
  6. "A collaborative study on the malignant syndrome in Parkinson's disease and related disorders", 9, pp.31~41 (2003)
  7. "Withdrawal of levodopa and other risk factors for malignant syndrome in Parkinson's disease", 9, pp.25~30 (2003)
  8. "Parkinsonism-hyperpyrexia syndrome not related to antiparkinsonian treatment withdrawal during the 2003 summer heat wave", 252, pp.1116~1119 (2005)
  9. "Dopamine dysregulation syndrome in Parkinson's disease patients: from reward to penalty", 59, pp.733~734 (2006)
  10. "The serotonin syndrome", 352, pp.1112~1120 (2005)

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