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논문KCI 등재

파킨슨병 환자의 병적 도박

Pathologic Gambling in Parkinson Disease

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주제분류신경과학

초록

Pathologic gambling (PG) is an impulse control disorder (ICD) or dopamine dysregulation syndrome (DDS) in patients with Parkinson disease (PD). ICD/DDS is presumed to be related to dopaminergic treatment in PD. Although increasing number of patients with ICD/DDS is being reported, ICD/DDS such as PG has not been reported in Korean PD patients. We describe a PD patient who developed PG secondary to dose adjustment of levodopa and pramipexole. His symptoms was controlled by reducing the dopaminergic drugs and adding a small amount of atypical antipsychotics.

Abstract

Pathologic gambling (PG) is an impulse control disorder (ICD) or dopamine dysregulation syndrome (DDS) in patients with Parkinson disease (PD). ICD/DDS is presumed to be related to dopaminergic treatment in PD. Although increasing number of patients with ICD/DDS is being reported, ICD/DDS such as PG has not been reported in Korean PD patients. We describe a PD patient who developed PG secondary to dose adjustment of levodopa and pramipexole. His symptoms was controlled by reducing the dopaminergic drugs and adding a small amount of atypical antipsychotics.

참고문헌 (10)

  1. Voon V, "Medication-related impulse control and repetitive behaviors in Parkinson’ disease", Curr Opin Neurol, 20, pp.484~492 (2007)
  2. Kaplan BJ, "Impulse-control disorder not elsewhere classified", In: Synopsis of psychiatry. 10th ed, pp.773~785 (2007), Williams & Wilkins
  3. Voon V, "Factors associated with dopaminergic drug-elated pathological gambling in Parkinson disease", Arch Neurol, 64, pp.212~216 (2007)
  4. Kim KH, "Psycho-Social Characteristics of Korean Gamblers and Predictors of Problem and Pathological Gambling", Kor J Health Psy, 9, pp.285~320 (2004)
  5. Kim KH, "Epidemiological Study of Pathological Gambling in South Korea: A Comparison of the KNODS, KMAGS, and the KSOGS", Kor J Health Psy, 10, pp.227~242 (2005)
  6. Grosset KA, "gambling on dopamine agonist: not such a rarity", Mov Disord, 21, pp.2206~2208 (2006)
  7. Avanzi M, "Prevalence of pathological gambling in patients with Parkinson’s disease", Mov Disord, 21, pp.2268~2072 (2006)
  8. Rodriguez-Oroz MC, "Bilateral deep brain stimulation in Parkinson’s disease: a multicentre study with 4 years follow-up", Brain, 128, pp.2240~2249 (2005)
  9. Krack P, "Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson’s disease", N Engl J Med, 349, pp.1925~1934 (2003)
  10. Chung SJ, "Bilateral effects of unilateral subthalamic nucleus deep brain stimulation in advanced Parkinson’s disease", Eur Neurol, 56, pp.127~132 (2006)

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