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국소 대뇌 허혈 및 재관류 후 생쥐 모델에서 활성 산소 제거제(MnTBAP)에 의한 Endonuclease G의 조기 핵 내 이동방지 및 뇌경색 감소

Treatment with MnTBAP Protects Against Early Nuclear Translocation of Endonuclease G and Reduces Cerebral Infarction after Focal Cerebral Ischemia/Reperfusion in Mice

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참고문헌

주제분류신경과학

참고문헌 (32)

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  3. "Oxygen radicals in focal cerebral ischemia", pp.59~65
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  5. "Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice", 19, pp.3414~3422 (1999)
  6. "Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency", 18, pp.205~213 (1998)
  7. "Caspases as treatment targets in stroke and neurodegenerative diseases", 45, pp.421~429 (1999)
  8. "Overexpression of copper", zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation, 2002, pp.22, 209~217
  9. "Molecular characterization of mitochondrial apoptosis- inducing factor", 397, pp.441~446 (1999)
  10. "Nuclear translocation of apoptosis inducing factor and subsequent DNA fragmentation by reactive oxygen species after permanent focal cerebral ischemia in mice", 7, pp.214~223 (2005)
  11. "Metalloporphyrin-based superoxide dismutase mimic attenuates the nuclear translocation of apoptosis- inducing factor and the subsequent DNA fragmentation after permanent focal cerebral ischemia in mice", 36, pp.2712~2717 (2005)
  12. "Early nuclear translocation of endonuclease G and subsequent DNA fragmentation after transient focal cerebral ischemia in mice", 386, pp.23~27 (2005)
  13. "Endonuclease G is an apoptotic DNase when released from mitochondria", 412, pp.95~99 (2001)
  14. "Toxic proteins released from mitochondria in cell death", 23, pp.2861~2874 (2004)
  15. "Structural and functional characterization of mitochondrial EndoG, a sugar non-specific nuclease which plays an important role during apoptosis", 338, pp.217~228 (2004)
  16. "Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I", 276, pp.48404~48409 (2001)
  17. "Overexpression of SOD1 in transgenic rats attenuates nuclear translocation of endonuclease G and apoptosis after spinal cord injury", 23, pp.595~603 (2006)
  18. "Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia", reperfusion in mice: implications for the production and role of superoxide radicals, 2002, pp.33, 809~815
  19. "Early decrease in dna repair proteins, Ku70 and Ku86, and subsequent DNA fragmentation after transient focal cerebral ischemia in mice", 32, pp.1401~1407 (2001)
  20. "Effect of suture size and carotid clip application upon blood flow and infarct volume after permanent and temporary middle cerebral artery occlusion in mice", 970, pp.131~139 (2003)
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  23. "Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption?", 23, pp.8733~8742 (2003)
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  26. "Endonuclease G is required for early embryogenesis and normal apoptosis in mice", 100, pp.15782~15787 (2003)
  27. "Role ofendonuclease G in neuronal excitotoxicity in mice", 364, pp.203~207 (2004)
  28. "Wood smoke extract induces oxidative stress-mediated caspase-independent apoptosis in human lung endothelial cells: role of AIF and EndoG", 289, pp.L739~L749 (2005)
  29. "Involvement of endonuclease G in nucleo- somal DNA fragmentation under sustained endogenous oxidative stress", 281, pp.6726~6733 (2006)
  30. "Influence of the antioxidants vitamin E and idebenone on retinal cell injury mediated by chemical ischemia, hypoglycemia, or oxidative stress", 26, pp.1405~1417 (1999)
  31. "A small-molecule-inducible Nrf2- mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo", 25, pp.10321~10335 (2005)
  32. "The cytosolic antioxidant copper", zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice, 2000, pp.20(shita n), 2817~2824

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