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다발경화증 유사 질환으로 나타난 HIV 감염증

Multiple Sclerosis-like Illness in a Patient With HIV Infection

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주제분류신경과학

초록

The spectrum of neurological complications that occurs in the setting of HIV-1 infection includes AIDS-dementia complex, progressive multifocal leukoencephalopathy, brain lymphoma, toxoplasma encephalitis, and cryptococcal meningitis. We present a 36-year-old man with subacute multifocal neurologic signs who had a 3-year history of HIV-1infection and a year history of left optic neuritis. The clinical presentation, CSF findings, and neuroradiological features in our patient were compatible with multiple sclerosis (MS), and hence he represented a rare case of HIV-related MS-like illness.

Abstract

The spectrum of neurological complications that occurs in the setting of HIV-1 infection includes AIDS-dementia complex, progressive multifocal leukoencephalopathy, brain lymphoma, toxoplasma encephalitis, and cryptococcal meningitis. We present a 36-year-old man with subacute multifocal neurologic signs who had a 3-year history of HIV-1infection and a year history of left optic neuritis. The clinical presentation, CSF findings, and neuroradiological features in our patient were compatible with multiple sclerosis (MS), and hence he represented a rare case of HIV-related MS-like illness.

참고문헌 (10)

  1. Berger JR, "Multiple sclerosis-like illness occurring with human immunodeficiency virus infection", Neurology, 39, pp.324~329 (1989)
  2. Duran E, "Multiple sclerosis-like illness in a HIV-1 patient", J Neurol, 251, pp.1142~1144 (2004)
  3. Graber P, "Multiple sclerosis-like illness in early HIV infection", AIDS, 14, pp.2411~2413 (2000)
  4. Corral I, "Relapsing and remitting leukoencephalopathy associated with chronic HIV infection", Eur Neurol, 48, pp.39~41 (2002)
  5. Polman CH, "Diagnostic criteria for multiple sclerosis: 2005 revisions to the McDonald Criteria", Ann Neurol, 58, pp.840~846 (2006)
  6. McArthur JC, "Neurological complications of HIV infection", Lancet Neurol, 4, pp.543~555 (2005)
  7. Narciso P, "Acute disseminated encephalomyelitis as manifestation of primary HIV infection", Neurology, 57, pp.1493~1496 (2001)
  8. Tenembaum S, "International Pediatric MS Study Group. Acute disseminated encephalomyelitis", Neurology, 68(16), pp.23~36 (2007)
  9. Franciotta D, "Oligoclonal IgG band patterns in inflammatory demyelinating human and mouse diseases", J Neuroimmunol, 200, pp.125~128 (2008)
  10. Silver B, "Fulminating encephalopathy with perivenular demyelination and vacuolar myelopathy as the initial presentation of human immunodeficiency virus infection", Arch Neurol, 54, pp.647~650 (1997)

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