진행성 소뇌 장애를 최초 증상으로 내원한 HIV 감염 1예
A Case of HIV Infection with Progressive Cerebellar Dysfunction as Initial Manifestation
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초록
HIV 감염은 다양한 신경학적 합병증이 동반되는 것으로 알려져 있으나 인지 기능의 장애 없이 소뇌 위축을 동반한 소뇌 장애 증상을 최초의 증상으로 나타나는 경우는 매우 드물다. 저자들은 국내에서 처음으로 소뇌에만 국한되어 위측 소견을 보이는 진행성 다발성 백질뇌병증에 의한 소뇌장애를 최초 증상으로 나타낸 HIV 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
Abstract
Human immunodeficiency virus (HIV) is known to affect the nervous system at all levels. Neurological complications of HIV occur at all stage of HIV infection, but cerebellar degeneration associated with HIV infection in the absence of cognitive impairment is exceedingly rare. We report a case of HIV infection, in which cerebellar degeneration was the first clinical manifestation. The brain MRI showed marked isolated cerebellar atrophy with severe cerebellar degeneration, but the patient did not have cognitive dysfunction. She was diagnosed as cerebellar form of progressive multifocal leukoencephalopathy with HIV infection. HIV infection should be considered in the diagnosis of any patient with cerebellar dysfunction of unclear origin.
참고문헌 (21)
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