Physical Activity and Prevalence of Rheumatoid Arthritis in Korean Adults with Prediabetes in the 2009-2013 National Health Cohort Study
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Background: Rheumatoid arthritis is highly prevalent in overweight patients with type 2 diabetes mellitus and can be reduced by physical activity via altered proinflammatory parameters. However, the association between the frequency of physical activity and the prevalence of rheumatoid arthritis in prediabetic patients remains unclear and was evaluated in this study. Methods: Utilizing the Korean National Health Insurance Sharing Service database, 58,391 adults, who met the research criteria and underwent a general medical check-up between 2009 and 2013, were selected for this study. To analyze the data, a logistic regression with a proc survey logistic procedure was used. Results: The study revealed that the cumulative rheumatoid arthritis prevalence was lower in prediabetic patients compared to that in the control group (OR, 0.64; 95% CI, 0.483-0.840; p=0.001). More frequent physical activity (>3 days/week) was significantly associated with a reduced rheumatoid arthritis prevalence in both groups (OR, 0.28; 95% CI, 0.039-0.521; p=0.044 vs. OR, 0.15; 95% CI, 0.063-0.237; p=0.007). Additionally, a 3.8-fold higher risk of rheumatoid arthritis development was observed in prediabetic adults with less frequent baseline physical activity (≤2 days/week). Overall, in prediabetes, the prevalence of rheumatoid arthritis was associated with the frequency of physical activity and not with the fasting plasma glucose levels. Conclusion: More frequent physical activity is associated with a low risk of developing rheumatoid arthritis in prediabetic patients. Thus, further studies are needed to confirm the clinical outcomes of frequent physical activity in rheumatoid arthritis prevention and control.
Abstract
Background: Rheumatoid arthritis is highly prevalent in overweight patients with type 2 diabetes mellitus and can be reduced by physical activity via altered proinflammatory parameters. However, the association between the frequency of physical activity and the prevalence of rheumatoid arthritis in prediabetic patients remains unclear and was evaluated in this study. Methods: Utilizing the Korean National Health Insurance Sharing Service database, 58,391 adults, who met the research criteria and underwent a general medical check-up between 2009 and 2013, were selected for this study. To analyze the data, a logistic regression with a proc survey logistic procedure was used. Results: The study revealed that the cumulative rheumatoid arthritis prevalence was lower in prediabetic patients compared to that in the control group (OR, 0.64; 95% CI, 0.483-0.840; p=0.001). More frequent physical activity (>3 days/week) was significantly associated with a reduced rheumatoid arthritis prevalence in both groups (OR, 0.28; 95% CI, 0.039-0.521; p=0.044 vs. OR, 0.15; 95% CI, 0.063-0.237; p=0.007). Additionally, a 3.8-fold higher risk of rheumatoid arthritis development was observed in prediabetic adults with less frequent baseline physical activity (≤2 days/week). Overall, in prediabetes, the prevalence of rheumatoid arthritis was associated with the frequency of physical activity and not with the fasting plasma glucose levels. Conclusion: More frequent physical activity is associated with a low risk of developing rheumatoid arthritis in prediabetic patients. Thus, further studies are needed to confirm the clinical outcomes of frequent physical activity in rheumatoid arthritis prevention and control.
참고문헌 (43)
- A-Homood IA, "Rheumatoid arthritis in patients with diabetes mellitus", Clin Rheumatol, 32, pp.527~533 (2013)
- Burner TW, "Diabetes and rheumatoid arthritis", Current Opinion in Rheumatology, 21(1), pp.50~54 (2009)
- Kim HR, "Rheumatic Manifestations of Diabetes", J Korean Diabetes, 14(4), pp.182~185 (2013)
- Origuchi T, "Increased incidence of prediabetes mellitus at a department of rheumatology: a retrospective study", Mod Rheumatol, 21, pp.495~499 (2011)
- Ruscitti P, "The role of IL-1β in the bone loss during rheumatoid arthritis", Mediators Inflamm, 2015, pp.1~10 (2015)
- Ursini F, "Prevalence of undiagnosed diabetes in rheumatoid arthritis: a OGTT study", Medicine, 95(7), pp.1~7 (2016)
- Ruscitti P, "Poor clinical response in rheumatoid arthritis is the main risk factor for diabetes development in the short-term: A 1-year, single-centre, longitudinal study", PLoS ONE, 12(7), pp.1~16 (2017)
- Arend WP, "Cytokine imbalance in the pathogenesis of rheumatoid arthritis: the role of interleukin-1 receptor antagonist", Semin Arthritis Rheum, 30(suppl(2)), pp.1~6 (2001)
- Lucas R, "Cytokine profiling of young overweight and obese female African American adults with prediabetes", Cytokine, 64(1), pp.310~315 (2013)
- Muñoz‐Cánoves P, "Interleukin‐6myokine signaling in skeletal muscle: a double‐edged sword?", FEBS J, 280(17), pp.4131~4148 (2013)
- Steensberg A, "IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans", Am J Physiol Endocrinol Metab, 285, pp.E433~E437 (2003)
- Sharif K, "Physical activity and autoimmune diseases: Get moving and manage the disease", Autoimmunity Reviews, 17(1), pp.53~72 (2018)
- Van den Ende CHM, "Effect of intensive exercise on patients with active rheumatoid arthritis: a randomised clinical trial", Ann Rheum Dis, 59(8), pp.615~621 (2000)
- Andonian BJ, "Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes", Arthritis Ther, 20, pp.2~9 (2018)
- Kraus WE, "Relationship between baseline physical activity assessed by pedometer count and newonset diabetes in the NAVIGATOR trial", BMJ Open Diab Res Care, 6, pp.1~7 (2018)
- Tierney M, "Physical activity in rheumatoid arthritis: a systematic review", J Phys Act Health, 9(7), pp.1036~1048 (2012)
- Sokka T, "Physical inactivity in patients with rheumatoid arthritis: data from twenty-one countries in a cross-sectional, international study", Arthritis Rheum, 59(1), pp.42~50 (2008)
- Giacomelli R, "Quality of life and unmet needs in patients with inflammatory arthropathies: results from the multicentre, observational RAPSODIA study", Rheumatology (Oxford), 54(5), pp.792~797 (2015)
- Lange E, "Aspects of activity with person-centred guidance influencing the transition to independent activity: a qualitative interview study among older adults with rheumatoid arthritis", Eur Rev Aging Phys Act, 16(4), pp.1~12 (2019)
- Sandoval-Rosario M, "Prevalence of Arthritis Among Adults with Prediabetes and Arthritis-Specific Barriers to Important Interventions for Prediabetes—United States, 2009-2016", MMWR, 67(44), pp.1238~1241 (2018)
- American Diabetes Association, "Standards of Medical Care in Diabetes-2019 A bridged for Primary Care Providers", Diabetes Care, 42(Suppl), pp.S1~S194 (2018)
- Kim KS, "Activity and T2DM: ACSM and ADA Joint Position Statement", J Korean Diabetes, 13, pp.61~68 (2012)
- Kucharski D, "Moderate-to-high intensity activity with person-centered guidance influences fatigue in older adults with rheumatoid arthritis", Rheumatol Int, 39(9), pp.1585~1594 (2019)
- Booth FW, "Lack of activity is a major cause of chronic diseases", Compr Physiol, 2(2), pp.1143~1211 (2012)
- Yates T, "Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial", Diabet Med, 32, pp.1090~1096 (2015)
- Hunter TM, "Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004-2014", Rheumatol Int, 37, pp.1551~1557 (2017)
- Silman AJ, "Epidemiology and genetics of rheumatoid arthritis", Arthritis Res, 4(suppl 3), pp.S265~S272 (2002)
- Rutledge GE, "CooRAinated Approaches to Strengthen State and Local Public Health Actions to Prevent Obesity, Diabetes, and Heart Disease and Stroke", Prev Chronic Dis, 25(15), pp.1~7 (2018)
- Steensberg A, "IL-6 and TNF-alpha expression in, and release from, contracting human skeletal muscle", Am J Physiol Endocrinol Metab, 283, pp.E1272~E1278 (2002)
- Krick S, "FGF23 Induction of OLinked N-Acetylglucosamine Regulates IL-6 Secretion in Human Bronchial Epithelial Cells", Front Endocrinol, 9, pp.1~10 (2018)
- Colberg SR, "American College of Sports Medicine; American Diabetes Association. Activity and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement", Diabetes Care, 33, pp.e147~e167 (2010)
- Narayan KM, "Lifetime risk for diabetes mellitus in the United States", JAMA, 290, pp.1884~1890 (2003)
- Jeon CY, "Physical activity of moderate intensity and risk of type 2 diabetes: a systematic review", Diabetes Care, 30, pp.744~752 (2007)
- Alberti KG, "Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention;National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity", Circulation, 120, pp.1640~1645 (2009)
- Bouchara C, "Familial aggregation of VO(2max)response to activity training: results from the HERITAGE Family Study", J Appl Physiol, 87, pp.1003~1008 (1999)
- Cocco G, "Physical activity with weight reduction lowers blood pressure and improves abnormal left ventricular relaxation in pharmacologically treated hypertensive patients", J Clin Hypertens (Greenwich), 13, pp.23~29 (2011)
- Bianchi G, "Physical activity is negatively associated with the metabolic syndrome in the elderly", QJM, 101, pp.713~721 (2008)
- Fora ES, "Sedentary behavior, physical activity, and the metabolic syndrome among U.S. adults", Obes Res, 13, pp.608~614 (2005)
- Booth FW, "Lack of activity is a major cause of chronic diseases", Compr Physiol, 2(2), pp.1143~1211 (2012)
- Kwun HS, "Current status and Need for a Korean Diabetes Prevention Study", Public Health Wkly Rep, 8, pp.746~753 (2015)
- Research report: National prevalence of diabetes and characteristic during 10 years based on National Health Insurance Service data, "Song SO", Kyungsung Munwhasa, 1~98, pp.National Health Insurance Service Ilsan Hospital Research, 2014-20-009 (2014)
- 허남욱, "국민건강영양조사를 이용한 한국인 관절염의 유병률 현황과 연도별 변화", 대한류마티스학회지, 15(1), pp.11~26 (2008), 대한류마티스학회
- Brenner PS, "Lies, Damned Lies, and Survey Self-Reports? Identity as a Cause of Measurement Bias", Soc Psychol Q, 79(4), pp.333~354 (2016)