The Prevalence of Osteoarthritis and Risk Factors in the Korean Population: The Sixth Korea National Health and Nutrition Examination Survey (VI-1, 2013)
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Background: Knee osteoarthritis is highly prevalent, especially among the elderly. However, its risk factors have not been well identified, especially in the Korean population. This study aimed to assess the epidemiologic characteris-tics and risk factors of knee osteoarthritis in the Korean population.Methods: Data of 2,280 (1,295 women) participants of the 2013 Korea National Health and Nutrition Examination Survey aged ≥50 years who underwent knee radiography were analyzed. According to the American College of Rheumatology clinical/radiographic classification criteria, knee osteoarthritis was defined as knee pain and radio-graphic knee osteoarthritis. The association between risk factors and knee osteoarthritis was analyzed using the chi-square test and binominal logistic regression.Results: The participants had an average age of 62.6 years; 56.8% of them were women. The average body mass in-dex was 24.2 kg/m2, and 296 (13%) participants were diagnosed with knee osteoarthritis. After adjustment for mul-tiple risk factors, age of ≥65 years (adjusted odds ratio [OR], 2.552; 95% confidence interval [CI], 1.868–3.486), fe-male sex (OR, 2.050; 95% CI, 1.275–3.295), obesity (body mass index, ≥25.0 kg/m2; OR, 1.563; 95% CI, 1.191–2.051), hypertension (OR, 1.394; 95% CI, 1.052–1.846), low educational level (lower than or equal to elementary school: OR, 4.761; 95% CI, 2.131–10.635; middle school: OR, 3.184; 95% CI, 1.375–7.369), and low strength exercise frequen-cy (<2 times/wk; OR, 1.829; 95% CI, 1.202–2.784) increased the risk of knee osteoarthritis.Conclusion: Old age, sex, obesity, hypertension, low educational level, and low strength exercise frequency were found to be risk factors for knee osteoarthritis.
Abstract
Background: Knee osteoarthritis is highly prevalent, especially among the elderly. However, its risk factors have not been well identified, especially in the Korean population. This study aimed to assess the epidemiologic characteris-tics and risk factors of knee osteoarthritis in the Korean population.Methods: Data of 2,280 (1,295 women) participants of the 2013 Korea National Health and Nutrition Examination Survey aged ≥50 years who underwent knee radiography were analyzed. According to the American College of Rheumatology clinical/radiographic classification criteria, knee osteoarthritis was defined as knee pain and radio-graphic knee osteoarthritis. The association between risk factors and knee osteoarthritis was analyzed using the chi-square test and binominal logistic regression.Results: The participants had an average age of 62.6 years; 56.8% of them were women. The average body mass in-dex was 24.2 kg/m2, and 296 (13%) participants were diagnosed with knee osteoarthritis. After adjustment for mul-tiple risk factors, age of ≥65 years (adjusted odds ratio [OR], 2.552; 95% confidence interval [CI], 1.868–3.486), fe-male sex (OR, 2.050; 95% CI, 1.275–3.295), obesity (body mass index, ≥25.0 kg/m2; OR, 1.563; 95% CI, 1.191–2.051), hypertension (OR, 1.394; 95% CI, 1.052–1.846), low educational level (lower than or equal to elementary school: OR, 4.761; 95% CI, 2.131–10.635; middle school: OR, 3.184; 95% CI, 1.375–7.369), and low strength exercise frequen-cy (<2 times/wk; OR, 1.829; 95% CI, 1.202–2.784) increased the risk of knee osteoarthritis.Conclusion: Old age, sex, obesity, hypertension, low educational level, and low strength exercise frequency were found to be risk factors for knee osteoarthritis.
참고문헌 (26)
- Urwin M, "Estimating the burden of musculoskeletal disorders in the community : the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation", Ann Rheum Dis, 57, pp.649~655 (1998)
- Thomas E, "The prevalence of pain and pain interference in a general population of older adults : crosssectional findings from the North Staffordshire Osteoarthritis Project(NorStOP)", Pain, 110, pp.361~368 (2004)
- Lawrence RC, "Estimates of the prevalence of arthritis and other rheumatic conditions in the United States : part II", Arthritis Rheum, 58, pp.26~35 (2008)
- Murphy L, "The impact of osteoarthritis in the United States: a population-health perspective", Am J Nurs, 112(3 Suppl 1), pp.S13~S19 (2012)
- Guccione AA, "Arthritis in nursing home residents : a validation of its prevalence and examination of its impact on institutionalization and functional status", Arthritis Rheum, 32, pp.1546~1553 (1989)
- Liu Q, "Knee osteoarthritis and all-cause mortality : the Wuchuan Osteoarthritis Study", Osteoarthritis Cartilage, 23, pp.1154~1157 (2015)
- Mili F, "Prevalence of arthritis : analysis of data from the US Behavioral Risk Factor Surveillance System, 1996-99", J Rheumatol, 29, pp.1981~1988 (2002)
- Veronese N, "Knee osteoarthritis and risk of hypertension : a longitudinal cohort study", Rejuvenation Res, 21, pp.15~21 (2018)
- Eitner A, "Pain sensation in human osteoarthritic knee joints is strongly enhanced by diabetes mellitus", Pain, 158, pp.1743~1753 (2017)
- Lee S, "Prevalence of knee osteoarthritis, risk factors, quality of life : the fifth Korean National Health And Nutrition Examination Survey", Int J Rheum Dis, 20, pp.809~817 (2017)
- Mazzuca SA, "Risk factors for early radiographic changes of tibiofemoral osteoarthritis", Ann Rheum Dis, 66, pp.394~399 (2007)
- Kellgren JH, "Radiological assessment of osteo-arthrosis", Ann Rheum Dis, 16, pp.494~502 (1957)
- Altman R, "Development of criteria for the classification and reporting of osteoarthritis:classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association", Arthritis Rheum, 29, pp.1039~1049 (1986)
- Eckstein F, "Recent advances in osteoarthritis imaging : the osteoarthritis initiative", Nat Rev Rheumatol, 8, pp.622~630 (2012)
- The Asia-Pacific perspective: redefining obesity and its treatment, "World Health Organization", Health Communications Australia, ~ (2000)
- Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, "Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)", JAMA, 285, pp.2486~2497 (2001)
- Hart DJ, "Association between metabolic factors and knee osteoarthritis in women : the Chingford Study", J Rheumatol, 22, pp.1118~1123 (1995)
- Felson DT, "Risk factors for incident radiographic knee osteoarthritis in the elderly : the Framingham Study", Arthritis Rheum, 40, pp.728~733 (1997)
- Slemenda C, "Reduced quadriceps strength relative to body weight : a risk factor for knee osteoarthritis in women", Arthritis Rheum, 41, pp.1951~1959 (1998)
- Blagojevic M, "Risk factors for onset of osteoarthritis of the knee in older adults : a systematic review and metaanalysis", Osteoarthritis Cartilage, 18, pp.24~33 (2010)
- Niu J, "Metabolic syndrome, its components, and knee osteoarthritis : the Framingham Osteoarthritis Study", Arthritis Rheumatol, 69, pp.1194~1203 (2017)
- Jorgensen KT, "Socio-demographic factors, reproductive history and risk of osteoarthritis in a cohort of 4.6 million Danish women and men", Osteoarthritis Cartilage, 19, pp.1176~1182 (2011)
- Lahmann PH, "Sociodemographic factors associated with long-term weight gain, current body fatness and central adiposity in Swedish women", Int J Obes Relat Metab Disord, 24, pp.685~694 (2000)
- Magnusson K, "Smoking and alcohol use are associated with structural and inflammatory hand osteoarthritis features", Scand J Rheumatol, 46, pp.388~395 (2017)
- Culvenor AG, "Defining the presence of radiographic knee osteoarthritis : a comparison between the Kellgren and Lawrence system and OARSI atlas criteria", Knee Surg Sports Traumatol Arthrosc, 23, pp.3532~3539 (2015)
- Zhang FF, "Vitamin D deficiency is associated with progression of knee osteoarthritis", J Nutr, 144, pp.2002~2008 (2014)
