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COVID-19 감염 후 발생한 시신경척수염범주질환

Neuromyelitis Optica Spectrum Disorder after COVID-19 Infection

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주제분류신경과학

초록

Coronavirus disease-19 (COVID-19) infection may be accompanied by various neurological complications. Among them, demyelinating disease involving the central nervous system has rarely been reported in association with COVID-19 infection. Herein, we report a case of newly diagnosed neuromyelitis optica spectrum disorder (NMOSD) right after COVID-19 infection. From our case, autoimmunity induced by para- and post-infectious immunologic responses or direct viral invasion might contribute to the development of NMOSD.

Abstract

Coronavirus disease-19 (COVID-19) infection may be accompanied by various neurological complications. Among them, demyelinating disease involving the central nervous system has rarely been reported in association with COVID-19 infection. Herein, we report a case of newly diagnosed neuromyelitis optica spectrum disorder (NMOSD) right after COVID-19 infection. From our case, autoimmunity induced by para- and post-infectious immunologic responses or direct viral invasion might contribute to the development of NMOSD.

참고문헌 (8)

  1. Wu Y, "Nervous system involvement after infection with COVID-19 and other coronaviruses", Brain Behav Immun, 87, pp.18~22 (2020)
  2. Avila M, "Multiple sclerosis and neuromyelitis optica spectrum disorder : onset following acute COVID-19 infection, a case series", Neurol Ther, 12, pp.319~327 (2023)
  3. Mirmosayyeb O, "Post COVID-19 infection neuromyelitis optica spectrum disorder(NMOSD) : a case report-based systematic review", Mult Scler Relat Disord, 60, pp.103697~ (2022)
  4. Wingerchuk DM, "International consensus diagnostic criteria for neuromyelitis optica spectrum disorders", Neurology, 85, pp.177~189 (2015)
  5. Kim HK, "Neurological manifestations in patients with COVID-19 : experiences from the central infectious diseases hospital in South Korea", J Clin Neurol, 17, pp.435~442 (2021)
  6. Ariño H, "Neuroimmune disorders in COVID-19", J Neurol, 269, pp.2827~2839 (2022)
  7. Sohn SY, "A case of optic neuritis after COVID-19 infection", JMSNI, 13, pp.16~18 (2022)
  8. Ismail II, "Association of CNS demyelination and COVID-19infection : an updated systematic review", J Neurol, 269, pp.541~576 (2022)

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