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KERD
논문KCI 등재

급성 세균뇌척수염 의심 질환으로 발현한 시신경척수염범주질환

Relapse of Neuromyelitis Optica Spectrum Disorder Presented with Suspected Bacterial Meningomyelitis

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초록

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory demyelinating disease. Anti-aquaporin-4 antibodies serve as a specific biomarker, while other factors including antecedent infection may also play a role in the development of NMOSD. Abnormal cerebrospinal fluid (CSF) findings such as leukocytosis with concentration >50/mm3 are one of the characteristics of NMOSD, but these were not specific for identifying other infective neurological diseases. Here we describe a rare case of NMOSD with CSF findings suggestive of bacterial meningomyelitis.

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory demyelinating disease. Anti-aquaporin-4 antibodies serve as a specific biomarker, while other factors including antecedent infection may also play a role in the development of NMOSD. Abnormal cerebrospinal fluid (CSF) findings such as leukocytosis with concentration >50/mm3 are one of the characteristics of NMOSD, but these were not specific for identifying other infective neurological diseases. Here we describe a rare case of NMOSD with CSF findings suggestive of bacterial meningomyelitis.

참고문헌 (9)

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  5. Li X, "Suspected bacterial meningomyelitis : the first presenting clinical feature of neuromyelitis optica spectrum disorder", J Neuroimmunol, 309, pp.68~71 (2017)
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  7. He M, "Suspected bacterial meningoencephalomyelitis as the trigger or presentation of neuromyelitis optica spectrum disorder flare", Mult Scler Relat Disord, 30, pp.38~41 (2019)
  8. Ghezzi A, "Clinical characteristics, course and prognosis of relapsing Devic's Neuromyelitis Optica", J Neurol, 251, pp.47~52 (2004)
  9. Milano E, "Neuromyelitis optica : importance of cerebrospinal fluid examination during relapse", Neurol Sci, 24, pp.130~133 (2003)

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