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하추체정맥동 채혈 검사 후 다발적 혈전 현상을 동반한 쿠싱병

Cushing’s Disease Complicated with Multiple Thrombotic Phenomena Following Inferior Petrosal Sinus Sampling

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초록

Cushing’s syndrome is an endocrinologic disorder that occurs due to an excessive secretion of adrenal cortex-stimulating hormones or an overproduction of cortisol in the adrenal glands. Patients present with a variety of clinical symptoms such as obesity, hypertension, impaired glucose tolerance, and cardiovascular complications have been known for major contributors to the mortality. The inferior petrosal sinus sampling (IPSS) test is a useful diagnostic tool for identifying the source of Cushing’s disease. This procedure involves process of collecting samples through venous access and is generally considered safe. Here, we present 44-yearold patient diagnosed with Cushing’s disease presenting pulmonary thromboembolism and multiple embolic infarctions following IPSS.

Abstract

Cushing’s syndrome is an endocrinologic disorder that occurs due to an excessive secretion of adrenal cortex-stimulating hormones or an overproduction of cortisol in the adrenal glands. Patients present with a variety of clinical symptoms such as obesity, hypertension, impaired glucose tolerance, and cardiovascular complications have been known for major contributors to the mortality. The inferior petrosal sinus sampling (IPSS) test is a useful diagnostic tool for identifying the source of Cushing’s disease. This procedure involves process of collecting samples through venous access and is generally considered safe. Here, we present 44-yearold patient diagnosed with Cushing’s disease presenting pulmonary thromboembolism and multiple embolic infarctions following IPSS.

참고문헌 (10)

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  4. St-Jean M, "Hypercoagulability in Cushing’s syndrome : from arterial to venous disease", Best Pract Res Clin Endocrinol Metab, 35, pp.101496~ (2021)
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  9. Boscaro M, "Anticoagulant prophylaxis markedly reduces thromboembolic complications in Cushing’s syndrome", J Clin Endocrinol Metab, 87, pp.3662~3666 (2002)
  10. Wijewickrama PSA, "A challenging case of Cushing’s disease complicated with multiple thrombotic phenomena following transsphenoidal surgery : a case report", BMC Endocr Disord, 21, pp.29~ (2021)

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