Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma with Ectopic Cushing’s Syndrome
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Esthesioneuroblastoma as a source of ectopic Cushing’s syndrome is rare, and to the best of our knowledge, only 20 cases havebeen reported worldwide. A 46-year-old healthy man visited a local clinic for general weakness and hyposmia, and underwentexamination with serial endocrinological workup and brain imaging. 68Gallium-DOTA-TOC positron emission tomography scanwas helpful where diagnosis of sellar MRI and inferior petrosal sinus sampling were discordant. Combined transcranial and endoscopicendonasal approach surgery was performed, and a diagnosis of esthesioneuroblastoma was given.
Abstract
Esthesioneuroblastoma as a source of ectopic Cushing’s syndrome is rare, and to the best of our knowledge, only 20 cases havebeen reported worldwide. A 46-year-old healthy man visited a local clinic for general weakness and hyposmia, and underwentexamination with serial endocrinological workup and brain imaging. 68Gallium-DOTA-TOC positron emission tomography scanwas helpful where diagnosis of sellar MRI and inferior petrosal sinus sampling were discordant. Combined transcranial and endoscopicendonasal approach surgery was performed, and a diagnosis of esthesioneuroblastoma was given.
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