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한국 소아와 청소년에서 대사증후군의 유병률

Prevalence of the Metabolic Syndrome in Korean Children and Adolescents: Korea National Health and Nutrition Survey 2001

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주제분류가정의학

초록

연구배경: 대사증후군은 심혈관 질환의 위험 인자들로 중요하게 예방 관리되어야 한다. 특히 소아와 청소년기의 비만과 대사 이상은 성인으로까지 이어지는 경우가 많으나 아직 우리나라에서는 소아와 청소년의 대사증후군에 대한 연구가 거의 없는 상태로 이에 본 연구는 한국 소아와 청소년의 대사증후군의 유병률에 대하여 알아보고 관련요인을 파악하고자 하였다. 방법: 2001년 시행된 국민건강영양조사 자료 중 10~19세 1,090명(남자 567명, 여자 523명)을 대상으로 National Cholesterol Education Program Adult Treatment panel III (NCEP ATP III)의 대사증후군 기준을 변형 적용하여 성별, 인구사회학적 요인, 비만도 등에 따른 대사증후군의 유병률을 분석하고 다중 로지스틱 회귀 모형을 이용하여 성별, 인구사회학적 요인, 비만도에 따른 대사증후군의 교차비(odds ratio)를 구하여 대사증후군과 관련된 요인을 분석하였다. 결과: 10세에서 19세 사이의 한국 소아와 청소년의 대사증후군 유병률은 7.1% (남아 9.2%, 여아 4.8%)이며 과체중군 (body mass index (BMI)≥95th%), 과체중 위험군(85th%≤BMI<95th%), 정상체중군(BMI가 85th% 미만인 군)에서 유병률은 각각 36.6%, 11.2%, 2.5%였다(P<0.001). 다중 로지스틱 회귀모형에서 대사증후군의 위험은 남아(교차비 2.07, 95% 신뢰구간[1.20~3.58]), 과체중 위험군(교차비 4.87, 95% 신뢰구간[2.42~9.83]), 과체중군(교차비 23.31, 95% 신뢰구간[12.84~42.34])에서 의미있게 증가하였다. 결론: 한국 소아와 청소년의 대사증후군 유병률은 7.1%이며 과체중군에서는 36.6%로 대사증후군의 예방, 조기발견, 관리를 위한 중재는 소아기부터 이루어져야 하며 특히 과체중 소아에게 집중되어야 할 것으로 생각된다.

Abstract

Prevalence of the Metabolic Syndrome in Korean Children and Adolescents: Korea National Health and Nutrition Survey 2001Min Jeong Seo, M.D., Jeong Won Seong, M.D., Keun Joo Sohn, M.D., Byung Joon Ko, M.D., Jee Hye Han, M.D., Ph.D.*, Seon Mee Kim, M.D., Ph.D.†

참고문헌 (36)

  1. Reaven GM, "Banting lecture 1988. Role of insulin resistance in human disease.", Diabetes, 37(12), pp.1595~1607 (1988)
  2. Hjermann I, "The metabolic cardiovascular syndrome: syndrome X, Reaven’s syndrome, insulin resistance syndrome, atherothrombogenic syndrome", J Cardiovasc Pharmacol, 20(8), pp.S5~S10 (1992)
  3. Alberti KG, "Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.", Diabet Med, 15(7), pp.539~553 (1998)
  4. Balkau B, "Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR).", Diabet Med, 16(5), pp.442~443 (1999)
  5. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP), "Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III).", JAMA, 285(19), pp.2486~2497 (2001)
  6. 박혜순, "심혈관 위험 인자의 군집 현상과 관상동맥질환과의 관계", 가정의학회지, 19(10), pp.881~893 (1998)
  7. Isomaa B, "Cardiovascular morbidity and mortality associated with the metabolic syndrome.", Diabetes Care, 24(4), pp.683~689 (2001)
  8. Haffner SM, "Prospective analysis of the insulin-resistance syndrome (syndrome X)", Diabetes, 41(6), pp.715~722 (1992)
  9. The Asia-Pacific Perspective, "Redefining Obesity and Its Treatment." (2000), Sydney, Australia: Health Communications Australia Pty Limit
  10. 박혜순, "한국인에서 대사증후군의 유병률 및 관련 요인", 대한비만학회지, 12(1), pp.1~14 (2003)
  11. Laaksonen DE, "Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study.", Am J Epidemiol, 156(11), pp.1070~1077 (2002)
  12. Lakka HM, "The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.", JAMA, 288(21), pp.2709~2716 (2002)
  13. Report on 2001 National Health and Nutrition Survey. In: Ministry of Health and Social Welfare Gyeonggi-do, , ~ (2002)
  14. "Update on the 1987 Task Force Report on High Blood Pressure in children and adolescents: a working group report from the national high blood pressure education program. national high blood pressure education program working group on hypertension control in children and adolescents", Pediatrics, 98(4 Pt 1), pp.649~658 (1996)
  15. Cook S, "Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third national health and nutrition examination survey, 1988-1994.", Arch Pediatr Adolesc Med, 157(8), pp.821~827 (2003)
  16. Standard data regarding physical development of Korean children and teenages., "Rhe Korean Pediatric Society Health Statistics Committee", Seoul: The Korean Pediatric Society, ~ (1999)
  17. Cole TJ, "Establishing a standard definition for child overweight and obesity worldwide: international survey.", BMJ, 320(7244), pp.1240~1243 (2000)
  18. Duncan GE, "Prevalence and trends of a metabolic syndrome phenotype among U.S. Adolescents, 1999~2000.", Diabetes Care, 27(10), pp.2438~2443 (2004)
  19. Ford ES, "Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey.", JAMA, 287(3), pp.356~359 (2002)
  20. 박혜순, "한국인에서의 대사증후군의 역학", 대한비만학회지, 11(3), pp.194~203 (2002)
  21. Haffner SM, "Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?", JAMA, 263(21), pp.2893~2898 (1990)
  22. Ronnemaa T, "Serum insulin and other cardiovascular risk indicators in children, adolescents and young adults", Ann Med, 23(1), pp.67~72 (1991)
  23. Pereira MA, "Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study.", JAMA, 287(16), pp.2081~2089 (2002)
  24. Kearney PM, "Worldwide prevalence of hypertension: a systematic review", J Hypertens, 22(1), pp.11~19 (2004)
  25. Pi-Sunyer FX, "Health implications of obesity.", Am J Clin Nutr, 53(6), pp.S159~S603 (1991)
  26. Vanhala MJ, "Relative weight gain and obesity as a child predict metabolic syndrome as an adult", Int J Obes Relat Metab Disord, 23(6), pp.656~659 (1999)
  27. Guo SS, "The predictive value of childhood body mass index values for overweight at age 35 y", Am J Clin Nutr, 59(4), pp.810~819 (1994)
  28. Whitaker RC, "Predicting obesity in young adulthood from childhood and parental obesity.", N Engl J Med, 337(13), pp.869~873 (1997)
  29. Csabi G, "Presence of metabolic cardiovascular syndrome in obese children", Eur J Pediatr, 159((1-2), pp.91~94 (2000)
  30. Berenson GS, "Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study.", N Engl J Med, 338(23), pp.1650~1666 (1998)
  31. McGill HC Jr, "Obesity accelerates the progression of coronary atherosclerosis in young men", Circulation, 105(23), pp.2712~2718 (2002)
  32. McKeigue PM, "Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians", Lancet, 337(8938), pp.382~386 (1991)
  33. Hunt KJ, "Familial history of metabolic disorders and the multiple metabolic syndrome: the NHLBI family heart study.", Genet Epidemiol, 19(4), pp.395~409 (2000)
  34. Boyko EJ, "Features of the metabolic syndrome predict higher risk of diabetes and impaired glucose tolerance: a prospective study in Mauritius.", Diabetes Care, 23(9), pp.1242~1248 (2000)
  35. Lee WY, "Effects of smoking, alcohol, exercise, education, and family history on the metabolic syndrome as defined by the ATP III.", Diabetes Res Clin Pract, 67(1), pp.70~77 (2005)

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