논문KCI 등재
대사증후군과 산화스트레스, 항산화제
Metabolic Syndrome and Oxidative Stress, Antioxidants
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초록
대사증후군 발생에 산화스트레스가 관계가 있다는 사실이 밝혀지고 있다. 대사증후군 환자에서 산화스트레스가 증가되어있고 지방세포에서 산화스트레스 생성이 늘어나 대사증후군을 유발시키는 것으로 생각되고 있다. 이와 같이 대사증후군의 병인으로 산화스트레스가 제시되고 있어 항산화제의 역할이 있을 것으로 생각된다. 대사증후군의 구성 요인인 당뇨나 혈압 각각에 대한 항산화제의 효과에 대한 연구 결과를 검토한 결과 일차 예방의 측면에서 도움이 되는 부분도 있으나 고위험군에서 항산화제를 복용하는 것에 대한 근거가 충분하다고 보기는 힘들다. 또한 미세영양소의 정확한 필요량과 각각의 상호 작용이 잘 알려져 있지 않다. 따라서 현재로서는 항산화제가 풍부한 식사 패턴을 유지하며 생활습관을 개선하는 것이 대사증후군 예방과 치료에 최선의 방법이다.
참고문헌 (84)
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