성인의 과민성방광증후군의 관련 요인 및 삶의 질
The Relating Factor and Quality of Life of Overactive Bladder in Adults
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연구배경: 과민성방광증후군(overactive bladder syndrome)은 일차 의료에서 흔하게 접할 수 있는 질환이며 과민성방광증 후군의 증상은 삶의 질에 부정적 영향을 미치게 된다. 그러나 성인에서의 과민성방광증후군과 관련된 인자 및 삶의 질에 대한 정보가 미흡한 실정이다. 따라서 본 연구에서는 성인에 서의 과민성방광증후군의 관련 인자를 찾고, 과민성방광증후 군의 삶의 질을 측정하고자 한다. 방법: 2008년 10월 1일부터 12월 31일까지 서울 및 충주 일개 대학병원을 방문한 20세 이상의 환자 396명을 대상으로 인구 학적 특성을 묻는 설문지와 Overactive Bladder Questionnaire (OAB-q)를 시행하였고, 최종적으로 설문 누락이나 통계 불가 한 69명(17.4%)을 제외한 327명을 대상으로 과민성방광증후 군의 관련 인자 및 삶의 질과의 연관성에 대하여 통계 분석하 였다. 결과: 총 327명 중, 과민성방광증후군으로 진단된 수는 38 (11.6%)명이었다. 과민성방광증후군은 연령대(P=0.007), 심 부전증 약제 복용력(P=0.023), 전립선비대증 약제 복용력 (P=0.002) 및 우울증 약제 복용력(P=0.008) 등과 관련 있는 것 으로 나왔으며, 이를 연관 변수로 보정한 결과 전립선비대 증 약제 복용력(P=0.042; OR=8.757) 및 우울증 약제 복용력 (P=0.005; OR=9.977)과 연관성 있는 것으로 나왔다. 과민성방 광증후군으로 진단된 군에서 정상인 군에 비하여 삶의 질이 확실히 감소함을 알 수 있었다. 결론: 성인에서 과민성방광증후군은 일반적으로 흔하게 접 할 수 있는 질병이며, 전립선비대증 약제 복용력 및 우울증 약 제 복용력이 있는 경우 더 흔하게 관찰되었고, 과민성방광증 후군과 관련된 증상들로 인하여 삶의 질의 감소가 나타났다. 과민성방광증후군으로 고통 받는 환자들을 적절히 파악하고, 관련인자를 분석하여 예방책과 치료에 관심을 가져야 할 것 이다.
Abstract
Background: Overactive bladder syndrome (OAB) is a common disorder in primary care that affects negatively on the quality of life of outpatients. However, little information is available on related factors and the quality of life in adults with overactive bladder. The purpose of this study was to fi nd related factors of overactive bladder and to measure the quality of life in adults with overactive bladder. Methods: Among the people who visited a hospital in Seoul and Chung-ju for a health examination or primary care between October 1 and December 31, 2008, we selected 327 participants over 20 years old. We measured their Overactive Bladder Questionnaire (OAB-q), took medical history and reviewed their demographic data. The relationship between OAB, other independent variables and health related quality of life (HRQL) were analyzed. Results: Of 327 respondents, the prevalence of OAB in adults was 38 (11.6%). The factors related to OAB were age (P = 0.007), history of prescription for congestive heart failure (P = 0.023), benign prostatic hyperplasia (BPH) (P = 0.002), and depression (P = 0.008). OAB was signifi cantly associated with BPH medication (P = 0.042; OR = 8.757) and depression medication (P = 0.005; OR = 9.977) in multivariable logistic regression analysis. In each T-test analysis, OAB decreased in HRQL. Conclusion: OAB is a common disorder in adults, history of BPH medication and depression medication is more common in OAB. The symptoms that were suggestive of OAB were affected negatively on the quality of life in adults. Effective health care polices and prompt management of OAB should be implemented.
참고문헌 (27)
- Abrams P, "The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society", Neurourol Urodyn, 21, pp.167~178 (2002)
- 김욱현, "젊은 여성에서 과민성방광과 요실금의 유병률 및 삶의 질", Korean Journal of Urology, 45(6), pp.543~550 (2004), 대한비뇨기과학회
- Milsom I, "How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study", BJU Int, 87, pp.760~766 (2001)
- Stewart WF, "Prevalence and burden of overactive bladder in the United States", World J Urol, 20, pp.327~336 (2003)
- Chen GD, "Prevalence and correlation of urinary incontinence and overactive bladder in Taiwanese women", Neurourol Urodyn, 22, pp.109~117 (2003)
- Homma Y, "An epidemiological survey of overactive bladder symptoms in Japan", BJU Int, 96, pp.1314~1318 (2005)
- Moorthy P, "Prevalence of overactive bladder in Asian men: an epidemiological survey", BJU int, 93, pp.528~531 (2004)
- "Int Urogynecol J", 2001, S169~
- Kim UH, "The prevalence of overactive bladder syndrome and urinary incontinence in young and middle aged women", J Korean Continence Soc, 7, pp.9~14 (2003)
- Matza LS, "Test-retest reliability of four questionnaires for patients with overactive bladder: the overactive bladder questionnaire (OAB-q), patient perception of bladder condition (PPBC), urgency questionnaire (UQ), and the primary OAB symptom questionnaire (POSQ)", Neurourol Urodyn, 24, pp.215~225 (2005)
- Choi JB, "Voiding dysfunction in women: incontinence and overactive bladder", Korean J Fam Med, 30(3), pp.S127~S132 (2009)
- Cooyne KS, "Validation of an OAB screener in a primary care patient population in the US", 34th Joint Meeting of the International Continence Society and the International UroGynecological Association; 2004 Aug 23-27; Paris, France (2004), The International Continence Society
- Cheung WW, "Prevalence, evaluation and management of overactive bladder in primary care", BMC Fam Pract, 10, pp.8~ (2009)
- Coyne KS, "The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey", Value Health, 7, pp.455~463 (2004)
- Wennberg AL, "A longitudinal population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in women", Eur Urol, 55, pp.783~791 (2009)
- 이규성, "과민성방광", Korean Journal of Urology, 48(12), pp.1191~1208 (2007), 대한비뇨기과학회
- Sampselle CM, "Urinary incontinence predictors and life impact in ethnically diverse perimenopausal women", Obstet Gynecol, 100, pp.1230~1238 (2002)
- Hannestad YS, "Are smoking and other lifestyle factors associated with female urinary incontinence? The Norwegian EPINCONT Study", BJOG, 110, pp.247~254 (2003)
- Melville JL, "Urinary incontinence in US women: a population-based study", Arch Intern Med, 165, pp.537~542 (2005)
- Chobanian AV, "The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report", JAMA, 289, pp.2560~2572 (2003)
- Ekundayo OJ, "Association of diuretic use and overactive bladder syndrome in older adults: a propensity score analysis", Arch Gerontol Geriatr, 49, pp.64~68 (2009)
- Hunt SA, "ACC", AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American college of cardiology, Circulation, pp.2005, 112[DOI]
- Yamaguchi C, "Overactive bladder in diabetes: a peripheral or central mechanism?", Neurourol Urodyn, 26, pp.807~813 (2007)
- Stewart WF, "Prevalence and burden of overactive bladder in the United States", World J Urol, 20, pp.327~336 (2003)
- Melville JL, "Prevalence of comorbid psychiatric illness and its impact on symptom perception, quality of life, and functional status in women with urinary incontinence", Am J Obstet Gynecol, 187, pp.80~87 (2002)
- Coyne K, "Psychometric validation of an overactive bladder symptom and health-related quality of life questionnaire: the OAB-q", Qual Life Res, 11, pp.563~574 (2002)
- Oh SJ, "Healthrelated quality of life and sexual function in women with stress urinary incontinence and overactive bladder", Int J Urol, 15, pp.62~67 (2008)